Protein Alignment sut2 and SLC2A8

DIOPT Version :10

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_047279239.1
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 599
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 115/425 - (27%)
• Similarity: 189/425 - (44%)
• Gaps: 62/425 - (14%)

  Fly    78 SIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASA 142
            ::..:|...|......|.|:.|||..|::.||.||....:.|   ||:.:.||:.||.|.|:|..
Human   196 AVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVIT---AAQDVWMLLGGRLLTGLACG 257

  Fly   143 LIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMA 207
            :.....|:|:.|.|...:.|.:|....:.|..|||||      :|.|....|.:......:....
Human   258 VASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA------YLAGWVLEWRWLAVLGCVPPSL 316

  Fly   208 SLVLLWWFPESPRWLYL-HKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLC 271
            .|:|:.:.||:||:|.. |:|..|.:  ||..|.|.....|            :....:|.|...
Human   317 MLLLMCFMPETPRFLLTQHRRQEAMA--ALRFLWGSEQGWE------------DPPIGAEQSFHL 367

  Fly   272 SVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLL 336
            ::||...::.|.::..|..|.|||||:||:.||:.:|...|.|.|.:..  ::.:|...:..:.:
Human   368 ALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLA--SVVVGVIQVLFTAV 430

  Fly   337 GPLLIRRFPRRPLMMISCSMCALALLAMSLGLFF--------------------LERSESTV-LT 380
            ..|::.|..||.|:::|..:...:..|  .|.:|                    .:..:::| |.
Human   431 AALIMDRAGRRLLLVLSGVVMVFSTSA--FGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLA 493

  Fly   381 YFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSV-- 443
            :.....:..||.||.:|.|||.:.:.||:.....:.||..:..|.:|:..|||...|..|..|
Human   494 WLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLR 558

  Fly   444 -----WSSFAFIPCMCVCIYCLLLTWRYLPETRGR 473
                 |.:.||      ||:.:|.|...:|||:|:
Human   559 PYGAFWLASAF------CIFSVLFTLFCVPETKGK 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	MFS_GLUT_Class1_2_like	23..473	CDD:340915	114/423 (27%)
SLC2A8	XP_047279239.1	PHA03307	3..>196	CDD:223039	115/425 (27%)
		MFS	36..591	CDD:475125	115/425 (27%)