DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut2 and ght6

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_587739.1	Gene:	ght6 / 2538845	PomBaseID:	SPCC1235.13	Length:	535	Species:	Schizosaccharomyces pombe

Alignment Length:	529	Identity:	117/529 - (22%)
Similarity:	213/529 - (40%)	Gaps:	86/529 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKW--CQDILANEYDTIV-TAGQLDILWTSIVSI 79
            ::||:.:::       .|:.||........|...  .|...|:.||.:. |..........:|.:
pombe     7 IVMLVFVSM-------AGWMFGADTGSIGGITNMRDFQSRYADRYDPVTDTYSYSSARQGLLVGM 64

  Fly    80 YLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILF------TWCRAAKSLEMLMTGRFLGG 138
            ...|...|...|:.|.|::|::.| ::...|..::|::.      :|.:       :|..:...|
pombe    65 VNTGTTVGCLLSSPLGDRFGKRKC-IMGWTLVYITGVIVQLTTIPSWVQ-------MMVAKIWTG 121

  Fly   139 IASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLA---QVATLSHLLGSERLW--PYAL 198
            :....:....|.|..||:|..:.|::.....:.:|.||.:|   .:.|..:....|..|  |..:
pombe   122 LGIGALSVIAPGYQSESSPPHIRGAIVTTYQLFITLGIFIAACINMGTHKYTTHPEAQWRVPIGI 186

  Fly   199 S-FYSLLVMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQ-ELLEMKATLEA 261
            : .:.:|:...::.|   |||||:|.:..|:.... |.|.|..|...:..:.| |...::|.:||
pombe   187 NLLWGILMFFGMLFL---PESPRYLAVKGRNEECM-KILTRNAGLPADHPIMQKEYNAIQADVEA 247

  Fly   262 KSSSEVSSLCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGI 326
            :.:....|...:..| |:....||.....|.|||:|.|..|:|...:....|.:......|.|..
pombe   248 ELAGGPCSWPQIFSN-EIRYRTLLGMGVMAFQQLTGNNYFFYYGTQVFRGTGLNSPFLAALILDA 311

  Fly   327 GSFNLCTSLLGPL-LIRRFPRR-PLMM--ISCSMCALALLAMSLGLFFLERSEST-------VLT 380
            .:|. ||  .|.: ::..|.|| ||::  :..|:|  ..:..|:|...|.|...|       |:.
pombe   312 VNFG-CT--FGAIFVLEYFGRRGPLIVGGVWQSIC--FFIYASVGDRALTRPNGTSNHRAGAVMI 371

  Fly   381 YFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLL-QSVW 444
            .|...||.:|...:    .|.||.|..|......|....::.:..:|..||::....|.: .|:.
pombe   372 VFSCLFIFSFAQTW----APAAYVIVGESYPIRYRSKCAAVATASNWFWNFMISFFTPFISNSIG 432

  Fly   445 SSFAFIPCMC-VCIYCLLLTWRYLPETRG-----------------------REPKDVKLLMSQ- 484
            ..:.::...| :|  ..::.:.:..||:|                       |:.:|:|...|:
pombe   433 FKYGYVFAACNLC--AAIIIFLFAKETKGLTLEEINQLYLSNIKPWNTGAYQRDREDIKQSDSEK 495

  Fly   485 --GLSSKLN 491
              |.:|||:
pombe   496 ERGPTSKLH 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	107/501 (21%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	95/415 (23%)
ght6	NP_587739.1	MFS	10..453	CDD:119392	105/473 (22%)
ght6	NP_587739.1	Sugar_tr	11..469	CDD:278511	107/488 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910