DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and C35A11.4

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_504430.2	Gene:	C35A11.4 / 178921	WormBaseID:	WBGene00016431	Length:	515	Species:	Caenorhabditis elegans

Alignment Length:	475	Identity:	123/475 - (25%)
Similarity:	221/475 - (46%)	Gaps:	24/475 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PLLMLICLTVTLGTTIPVGYFFG---VLNAPA-EIIKKWCQDILANEYDTIVTAGQLDILWTSIV 77
            |...:||:.|.  |:|...:.||   ||..|: |....:....||..:|..::...|..:|:.:|
Worm     5 PSFRMICVAVI--TSIAGSFHFGFNLVLTNPSQEAFLNFMNQTLAKRFDGGLSDNTLQNIWSFVV 67

  Fly    78 SIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASA 142
            :|..:|.:.||....::.|..|||..|.||..:.|::|.:....:.....|:.:..|.:.|.:.:
Worm    68 AILFLGALAGSFSIRLIADWIGRKNGLYISIAVGVLAGGMSIASKFIPLFELYIASRIVMGWSVS 132

  Fly   143 LIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLW--PYALSFYSLLV 205
            :......::|.|::|.:..|::|:.|...|..|.:...|..:..:.|:|.||  .||.....:|.
Worm   133 VSLGLSALFLSEASPKQNRGAIGMMTGTCVQLGTVCGSVIAMPQIFGTEDLWWLIYATEIGIMLF 197

  Fly   206 MASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSL 270
            ..:  .|.:|||||.:|.......||::...........|.|.|  |.|:|.  |.|:|::...:
Worm   198 FGA--ALPFFPESPGFLIQRGATEAATKSIAYYYNCEIDEAEKH--LNEIKE--EQKNSTKNFKM 256

  Fly   271 CSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSL 335
            ..::|...|.....:..........||:..|..::..||.:.|.....|:..|..|...::.:|:
Worm   257 MDIVRKKSLRDKAFIGVVVTFAMSFSGVAVINAFAFDILKDTGLKVLEASLANDAISVVSMISSI 321

  Fly   336 LGPLLIRRFPRRPLMMISCS---MCALALLAMSLGLFFLERSESTVLTYFCAAFILTFILGFQLG 397
            :..:::.|..||||::||.:   :|.|.:.|:   :|...:.|:.||.:....||..|...|.||
Worm   322 VAAVIVDRNGRRPLLLISFAGILVCNLIIFAL---MFTFYKFENHVLGFILICFICIFTFFFALG 383

  Fly   398 LGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCF-PLLQSVWSSFAFIPCMCVCIYCLL 461
            .||:.|||.:||:..:.|..|.|..|:...:..|::...| |:...:..::::: .:.|......
Worm   384 PGPLCYFINAELVGQAARSAAQSWASVIQMLSRFVIVTAFLPMKNQLGEAWSYL-ILFVAPVAAS 447

  Fly   462 LTWRY--LPETRGREPKDVK 479
            |.:.|  ||||:.:.|.:|:
Worm   448 LVYLYFSLPETKNKNPFEVE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	119/461 (26%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	99/395 (25%)
C35A11.4	NP_504430.2	MFS_GLUT_Class1_2_like	13..461	CDD:340915	118/459 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157996
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28646
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.760