Protein Alignment sut2 and SLC2A12

DIOPT Version :9

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_660159.1
• Gene: SLC2A12 / 154091
• HGNCID: 18067
• Length: 617
• Species: Homo sapiens
• Alignment Length: 578
• Identity: 125/578 - (21%)
• Similarity: 229/578 - (39%)
• Gaps: 143/578 - (24%)

  Fly     9 PPKVNGWTPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILA---NEYDTIVTAGQLD 70
            ||...|......|..:|..:...: |||..|:::.....||    .:||   :|.:
Human    30 PPWARGCGMFTFLSSVTAAVSGLL-VGYELGIISGALLQIK----TLLALSCHEQE--------- 80

  Fly    71 ILWTSIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRF 135
                .:||..:||.:..|....||.|:|||:..:::||.|..:..::..   .:.|..:|:.||.
Human    81 ----MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLI---LSLSYTVLIVGRI 138

  Fly   136 LGGIASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQV-----ATLSHLLGSERLWP 195
            ..|::.:|...|..:|:.|.||....|.:.....:.:..|||.|.:     |.:.|  |    |.
Human   139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFH--G----WK 197

  Fly   196 YALSFYSLLVMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLE 260
            |.......|.:...:.:::.|.|||:|.:..::.||| |.|.|||..:   :..:||..:|::|:
Human   198 YMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAAS-KVLGRLRALS---DTTEELTVIKSSLK 258

  Fly   261 AKSSSEVSSLCSVLRNSE-----LWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGF-SDGAA 319
            .:..   .|...:.|:.:     :.:.|.||...|.|.|.:    |.||:.::|.:.|| |:.||
Human   259 DEYQ---YSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPN----ILFYASTVLKSVGFQSNEAA 316

  Fly   320 TWLNLGIGSFNLCTSLLGPLLIRRFPRRPLMMISCSMCALALLAMSL------------------ 366
            :..:.|:|...:.:::...||:.....:..:.|..|:.|.:|:.|.:
Human   317 SLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNS 381

  Fly   367 ------------------------------------GLFFL-----ERSEST------------- 377
                                                .|..|     :|.|:|
Human   382 INQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTE 446

  Fly   378 ------------VLTYFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGN 430
                        .|.:...|.:|.::..|.:||||:.:.:.||:.....|..||::.|..:|..|
Human   447 YQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGIN 511

  Fly   431 FLVGMCF----PLLQSVWSSFAFIPCMCVCIYCLLLTWRYLPETRGREPKDVKLLMSQ 484
            .|:.:.|    .|:...|..|.:   ..:.:..||....::|||:|...:.:.:.:::
Human   512 LLISLTFLTVTDLIGLPWVCFIY---TIMSLASLLFVVMFIPETKGCSLEQISMELAK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	120/551 (22%)
		MFS	76..466	CDD:119392	107/488 (22%)
SLC2A12	NP_660159.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Sugar_tr	44..561	CDD:306568	121/557 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144300
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840