DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut2 and slc2a11

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_004910639.2	Gene:	slc2a11 / 100496562	XenbaseID:	XB-GENE-980809	Length:	508	Species:	Xenopus tropicalis

Alignment Length:	457	Identity:	144/457 - (31%)
Similarity:	235/457 - (51%)	Gaps:	8/457 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVSIYLI 82
            ||:.:| ...:|.|...||...::|||...|:|:..:.........:.:..:.::|:.|||:|.:
Frog    25 LLLTMC-AAGIGGTFQYGYNLTIINAPTMHIQKFVNETWLERNGQQLDSQVITLIWSIIVSVYPL 88

  Fly    83 GGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIFTA 147
            ||..|:..:..:..:.|||..|:.:::..::|.||....|.|||.||::.||.|.|:.|.:....
Frog    89 GGFLGALLAGPMAIRLGRKKSLLFNNLFVILSAILCGLSRPAKSFEMIVLGRILAGLNSGVSMNV 153

  Fly   148 QPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLVLL 212
            |||||.||||.:|.|:|.:.:......|::|.||..|..:||||..||:.|:..::..|..|.:|
Frog   154 QPMYLSESAPMKLRGTVAMSSAAFTALGLVLGQVIGLREILGSEECWPFLLASNAVPAMLQLFVL 218

  Fly   213 WWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLCSVLRNS 277
            .|.|||||:|.:..:|..:...||.||||.:   ::..|:.:|.|...|.......|||.::|..
Frog   219 PWLPESPRYLLIDLKDKDSCICALQRLRGHS---DLSLEMEQMLAEQAAIKGQRPKSLCELIREP 280

  Fly   278 ELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLLIR 342
            .|...:|.:....:..||.|.::::||:.||...||.......::.:|.||..|.||:...:.|.
Frog   281 TLRRQILTIVVLSSAMQLCGNDSMYFYASSIFQEAGIPLEKIQYVVIGTGSCELVTSITCTVFID 345

  Fly   343 RFPRRPLMMISCSMCALALLAMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLGPIAYFIGS 407
            |..||.|:|...|:.::..:...:.|  .::...:.:.|.....|..:||.|.:|...:...:..
Frog   346 RVGRRALVMGGYSLMSVWAVVFMVAL--SQQGHVSWMPYLSMVCIFAYILSFGIGPAGVTGIMPG 408

  Fly   408 ELLEDSPRPVA-MSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTWRYLPETR 471
            |:.:...||.| |..|||. ||..|::|:.||.:......|.|||.:.||:...|....:||||:
Frog   409 EIFDQMARPAAYMICGSLI-WIMLFVIGLAFPFILQGLGHFCFIPFLVVCVSTALYVGIFLPETK 472

  Fly   472 GR 473
            |:
Frog   473 GK 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	141/450 (31%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	126/390 (32%)
slc2a11	XP_004910639.2	MFS_GLUT_Class2	28..479	CDD:340990	142/454 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010