DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and slc2a3b

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_002667169.2	Gene:	slc2a3b / 100330897	ZFINID:	ZDB-GENE-121031-5	Length:	534	Species:	Danio rerio

Alignment Length:	501	Identity:	151/501 - (30%)
Similarity:	256/501 - (51%)	Gaps:	48/501 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQ------LDILWTSI 76
            |.::.|::..:..::..||..||:|||...::.:.:::      |:|..|:      :..||:..
Zfish    14 LCLMFCVSTAVIGSLQFGYNIGVINAPDVKVQNFFRNV------TLVRTGEPMDDYTVTTLWSVA 72

  Fly    77 VSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIAS 141
            |:|:..||:.||.....|.:|.|.:..:::|::|.::.|.|........|.|:|:.||.:.|:..
Zfish    73 VAIFNFGGMIGSLSVGALVNKLGGRKSMLLSNILALIGGGLMGLSSICSSYELLIVGRLVIGVFC 137

  Fly   142 ALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVM 206
            .|.....|||:.|.||:.|.|:.|....:||..|||:||:..|..||||:.|||..|:..:|..:
Zfish   138 GLSTGLTPMYVGEIAPTALRGAFGTLHQLGVVIGILVAQILGLESLLGSQTLWPLLLALTALPAV 202

  Fly   207 ASLVLLWWFPESPRWLY--LHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSS 269
            ...::|.:..||||:|.  |:|.|.|  .:||..|||.:   :|..::.|||......|..:..|
Zfish   203 IQSIMLIFCLESPRYLLISLNKEDEA--RQALTSLRGHS---DVEDDIREMKDEAMKMSMEKRVS 262

  Fly   270 LCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTS 334
            :..:.||.....|:::....|.:||||||||:.:||..|..|||.::  ..:..:|:|..|...:
Zfish   263 IPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRNAGITE--PVFATIGMGVVNTVFT 325

  Fly   335 LLGPLLIRRFPRRPLMMI---SCSMCALALLAMSLGLFFLERSESTVLTYFCAAF---------- 386
            ::...|:.|..||.|.:|   ..:.|.| |:.:||.|...|..::.:|....|..
Zfish   326 VVSLFLVERAGRRTLHLIGLTGMTFCVL-LVTISLKLVDSEIEKAKLLQNGTAIIDSASPSEGIS 389

  Fly   387 ---------ILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQS 442
                     :..|:..|::|.|||.:||.:||....|||.||::....:|..:||||:.||:|..
Zfish   390 TVKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASFLVGLLFPILSK 454

  Fly   443 VWSSFAFIPCMCVCIYCLLLTWRYLPETRGREPKDVKLLMSQGLSS 488
            ...::.||..:.:.:..::.|:..:|||:||..:|:    :.|.|:
Zfish   455 KIGAYVFIIFLILLVVFIVFTYFRVPETKGRTFEDI----ASGFSN 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	145/479 (30%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	129/413 (31%)
slc2a3b	XP_002667169.2	Sugar_tr	19..494	CDD:278511	148/492 (30%)
slc2a3b	XP_002667169.2	MFS	66..479	CDD:119392	131/420 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.800