DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and slc2a1b

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_002662574.1	Gene:	slc2a1b / 100321338	ZFINID:	ZDB-GENE-090915-1	Length:	489	Species:	Danio rerio

Alignment Length:	464	Identity:	141/464 - (30%)
Similarity:	247/464 - (53%)	Gaps:	26/464 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVSIYLIG 83
            |||...|..:| ::..||..||:|||.:||:.:..:.....:..:::...:..||:..|:|:.:|
Zfish    11 LMLAVGTAVIG-SLQFGYNTGVINAPQKIIEAFYNETWTARHGDMISKTTMTTLWSLSVAIFSVG 74

  Fly    84 GICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIFTAQ 148
            ||.||....:..:::||:..:::::||..::..|..:.:.|.|.|||:.|||:.|:.|.|.....
Zfish    75 GIVGSFSVGLFVNRFGRRNSMLMANVLAFIAAALMGFSKMAASWEMLIIGRFVVGLYSGLSTGFV 139

  Fly   149 PMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLVLLW 213
            |||:.|.||:.|.|::|....:|:..|||:|||..:..::|:..:||:.|.|..:..:....||.
Zfish   140 PMYVGEVAPTALRGALGTLHQLGIVVGILMAQVFGMEAIMGNATMWPFLLGFTFIPALVQCCLLP 204

  Fly   214 WFPESPRWLYLHKRDSAASEKALLRLRG--------RNTEEEVHQELLEMKATLEAKSSSEVSSL 270
            ..|||||:|.:::.:.:.::..|.:|||        :..:||..|.:.|.|.|:.
Zfish   205 ICPESPRFLLINRNEESKAKSVLKKLRGTTDVSADMQEMKEESRQMMREKKVTIP---------- 259

  Fly   271 CSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSL 335
             .:.|:.....|:::....|.:||||||||||:||..|...||...  ..:..:|.|..|...::
Zfish   260 -ELFRSPLYRQPIVIAIMLQLSQQLSGINAIFYYSTKIFEKAGVQQ--PVYATIGAGVVNTAFTV 321

  Fly   336 LGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLGP 400
            :...::.|..||.|.::.....|.:.:.|::.:..||:.:  .::|.....|..|:..|::|.||
Zfish   322 VSLFVVERAGRRSLHLLGLLGMAGSAILMTIAIALLEKYD--WMSYMSIVAIFAFVAFFEIGPGP 384

  Fly   401 IAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYC-LLLTW 464
            |.:||.:||....|||.|.::....:|..||:|||||..::.|..::.|: ...|.:.| .:.|:
Zfish   385 IPWFIVAELFSQGPRPSAFAVAGFSNWTANFIVGMCFQYVEEVCGAYVFV-IFTVFLLCFFIFTY 448

  Fly   465 RYLPETRGR 473
            ..:|||:||
Zfish   449 FKVPETKGR 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	136/458 (30%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	120/398 (30%)
slc2a1b	XP_002662574.1	Sugar_tr	17..466	CDD:278511	138/458 (30%)
slc2a1b	XP_002662574.1	MFS	61..449	CDD:119392	122/403 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577182
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.000