DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and slc2a5

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001352581.1	Gene:	slc2a5 / 100006415	ZFINID:	ZDB-GENE-060222-2	Length:	511	Species:	Danio rerio

Alignment Length:	475	Identity:	147/475 - (30%)
Similarity:	254/475 - (53%)	Gaps:	18/475 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEY----DTIVTAGQLDILWTSI 76
            |.:|....|....|::...||...|:|:||..::::.:.|..:.|    |.::|     :||:..
Zfish    17 TLILAAASLVAGFGSSFQYGYNVAVVNSPAPEMQQFYRRIYVDRYGPMSDNLLT-----LLWSVT 76

  Fly    77 VSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIAS 141
            ||:|.:||..||...|.|.:|:||||.|:.:::..:|..|:......|.|.|:::..|||.||.:
Zfish    77 VSMYPLGGFFGSLMVAPLVNKFGRKGTLLFNNIFSIVPAIMMGVSEVAGSFEIIIVARFLVGICA 141

  Fly   142 ALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVM 206
            .|.....||||.|.||....|:||:...:.:|.|||:||:..:..:||::..||..|....:...
Zfish   142 GLSSNVVPMYLGEIAPKNYRGAVGIVPQLFITVGILVAQIFGIRSILGNKEGWPIMLGLTGIPAA 206

  Fly   207 ASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLC 271
            ..|:||.:||||||::.:.|.|...:.|.|.||||.   |:|.:||.||:...:::.:....||.
Zfish   207 IELLLLPFFPESPRYMLIQKGDEKTARKGLQRLRGC---EDVDEELCEMRVEEQSERAEGRLSLL 268

  Fly   272 SVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLL 336
            ::.....|...||.|......|||||:|||::|:.||.::||.|:....::.:|.|:.|:..::.
Zfish   269 NLFTFRSLRWQLLSVIFMNMGQQLSGVNAIYYYADSIYSSAGVSEDHVQYVTVGTGAVNVFMTIT 333

  Fly   337 GPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTV--LTYFCAAFILTFILGFQLGLG 399
            ...::.:..|:.|::|...:|..|.:.:::.|:|    ::|:  :.|.....::.:::|..:|..
Zfish   334 AVFIVEKSGRKLLLLIGFGICCAACVILTIALYF----QTTLDWIPYVSIVCVIVYVIGHAIGPS 394

  Fly   400 PIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTW 464
            ||...|.:|:...|.||.|..:.....|:.||.||:.||.|:.....::||...|:|:..|:..|
Zfish   395 PIPTVITTEMFRQSSRPPAFMVAGSVHWLSNFTVGLVFPFLERGLGPYSFIIFACICLATLIYIW 459

  Fly   465 RYLPETRGREPKDVKLLMSQ 484
            ..:|||:.:...:...|.:|
Zfish   460 IVIPETKNKTFLETSKLFAQ 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	143/455 (31%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	126/391 (32%)
slc2a5	NP_001352581.1	Sugar_tr	23..477	CDD:306568	143/465 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.960