Protein Alignment sut3 and HXT1

DIOPT Version :10

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 120/515 - (23%)
• Similarity: 214/515 - (41%)
• Gaps: 105/515 - (20%)

  Fly    13 VLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESV---------LERYSSRLGDSQ---MTII 65
            |.|| |:.|        |||      .||..|...::         |.|:..:..|..   ..:.
Yeast    65 VSIC-CVMV--------AFG------GFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVR 114

  Fly    66 MSTVVSIF----LIGGMLGAPFAPIFSARLGRRGILTL--SGLLLLVSCICQLFCRMANSIEMLL 124
            ...:||||    .|||::.|....::..|:|...::.:  .|:::.::.|        |......
Yeast   115 TGLIVSIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQIASI--------NKWYQYF 171

  Fly   125 LGRLIGGLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKL--- 186
            :||:|.||....|....||.:.|:||:|:.|::.....:.:|.||.||...:|    ||:..
Yeast   172 IGRIISGLGVGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNF----GTKNYSNS 232

  Fly   187 --WPYALSGSAIFVLIGLAPIFWFPESPRFLMSQGRREKARVTLMRLRR---DEGRVNAEMAEFE 246
              |...|.....:.|..:..:.:.|||||:|:..||.::||.:|.::.:   |...:..|:...|
Yeast   233 VQWRVPLGLCFAWALFMIGGMMFVPESPRYLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIE 297

  Fly   247 VS--------STDEGQV----------TMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSI 293
            .|        :...|::          ||..::..|              :||::|.:..::|..
Yeast   298 ASVEEMRAAGTASWGELFTGKPAMFQRTMMGIMIQS--------------LQQLTGDNYFFYYGT 348

  Fly   294 EIFTQSGFTAAVAMWLNFALGLLNFISALMGPWLMRSFNRR--LMM-TISCLCSAIFLVLLVVGL 355
            .:|...|.:.:....:.|  |::||.|.....:.:..|.||  ||. .:..:|  .::|...||:
Yeast   349 IVFQAVGLSDSFETSIVF--GVVNFFSTCCSLYTVDRFGRRNCLMWGAVGMVC--CYVVYASVGV 409

  Fly   356 ELM------STIHEFSFTC-IAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWL 413
            ..:      ....:.:..| |.|...||..|.....|..|.:.||.|....:...|::.|..||:
Yeast   410 TRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIAYVVISECFPLRVKSKCMSIASAANWI 474

  Fly   414 ANFVLNMIFPTLNSATG---PFVFLLCVVFCAYGFLLTYRYLPETRNRDAKDVAQLMENG 470
            ..|:::...|.:..|..   .:||:.|:|| ||.::  :.::|||:....::|..:...|
Yeast   475 WGFLISFFTPFITGAINFYYGYVFMGCMVF-AYFYV--FFFVPETKGLSLEEVNDMYAEG 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	MFS_GLUT_Class1_2_like	16..458	CDD:340915	116/498 (23%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	117/507 (23%)