Protein Alignment sut3 and ITR2

DIOPT Version :10

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 503
• Identity: 115/503 - (22%)
• Similarity: 211/503 - (41%)
• Gaps: 83/503 - (16%)

  Fly    19 ITVGTVIPV-GYAFGVMNAPSAFIRSWIMESV---LERYSSRLGDSQMTIIMSTVVSIFLIGGML 79
            ||:..|..: |:.||.   .:.:|.|.:: |:   |:......|:.::      :.:...:|.::
Yeast   110 ITLTFVASISGFMFGY---DTGYISSALI-SINRDLDNKVLTYGEKEL------ITAATSLGALI 164

  Fly    80 GAPFAPIFSARLGRRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLIGGLAAALIYATQPMY 144
            .:..|...:...|||..|..|.|:.|:..|.|:   .|:....:..||||.|....:.....|::
Yeast   165 TSVGAGTAADVFGRRPCLMFSNLMFLIGAILQI---TAHKFWQMAAGRLIMGFGVGIGSLISPLF 226

  Fly   145 LVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSAIFVLIGLAP----- 204
            :.|:||..:.|.:.|...:.|||    ||:.::....|..    :..:|..|.|.:.|.|
Yeast   227 ISEIAPKMIRGRLTVINSLWLTG----GQLIAYGCGAGLN----HVKNGWRILVGLSLIPTVLQF 283

  Fly   205 -IFWF-PESPRFLMSQGRREKARVTLMRLRRDEGRVNA----------EMAEFEVSSTDEGQVTM 257
             .|.| |::||:.:.:|..::|::.|.|     ..||.          |::....|...:..:|.
Yeast   284 SFFCFLPDTPRYYVMKGDLKRAKMVLKR-----SYVNTEDEIIDQKVEELSSLNQSIPGKNPITK 343

  Fly   258 KQVLCNSKLKLP-----LFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLN 317
            ...:......:|     |.|.|....:||.:|.:::.::|..||...||..:.|  ::..:...|
Yeast   344 FWNMVKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSA--VSIIVSGTN 406

  Fly   318 FISALMGPWLMRSFNRRLM-------MTISCLCSAI---FLVLLVVGLELMSTIHEFS---FTCI 369
            |:..|:..:.:....||.:       ||::.:..||   ||.:...|.:.:.....||   ...|
Yeast   407 FVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDGFSSWGIVII 471

  Fly   370 AFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTL---NSATGP 431
            .|:.:|...:.:|:|..|: ..||:|....|....:..:..||..:.|:...|.|:   .:.||.
Yeast   472 VFIIVYAAFYALGIGTVPW-QQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGT 535

  Fly   432 FVFL-----LCVVFCAYGFLLTYRYLPETRNRDAKDVAQLMENGFKSK 474
            |.|.     |..:||       |...||....:.::|..::::||..|
Yeast   536 FSFFAGVACLSTIFC-------YFCYPELSGLELEEVQTILKDGFNIK 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	MFS_GLUT_Class1_2_like	16..458	CDD:340915	111/485 (23%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	107/476 (22%)