DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and HXT8

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_012321.1	Gene:	HXT8 / 853216	SGDID:	S000003750	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	489	Identity:	115/489 - (23%)
Similarity:	214/489 - (43%)	Gaps:	55/489 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTIIMSTV-----VSIF 73
            ::|:|:..|..:. |:..|.:   |.|:.   ....|.|:.: ...|:.|..:|.|     ||||
Yeast    68 IMCLCMAFGGFMS-GWDTGTI---SGFVN---QTDFLRRFGN-YSHSKNTYYLSNVRTGLIVSIF 124

  Fly    74 LIGGMLGAPFAPIFSARLGRRGILTLSGLLLLVSCICQLFCRMANSIE---MLLLGRLIGGLAAA 135
            .:|..:|..|........||...|.:..::.:|..:.|:     .||:   ...:||:|.|:.|.
Yeast   125 NVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQI-----ASIDKWYQYFIGRIIAGIGAG 184

  Fly   136 LIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKL-----WPYALSGSA 195
            .|....||.:.|.||..:.|::.....:.:|..|.||...::    ||:..     |...|....
Yeast   185 SISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNY----GTKTYSNSVQWRVPLGLCF 245

  Fly   196 IFVLIGLAPIFWFPESPRFLMSQGRREKARVTLM---RLRRDEGRVNAEMAEFEVSSTDE----G 253
            .:.:|.:..:.:.|||||||:..|:.|:|:.:..   :|..|:..|.||: :..|:..:.    |
Yeast   246 AWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEI-DLLVAGVEAEEAMG 309

  Fly   254 QVTMKQVLC-NSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLN 317
            ..:.|::.. .:|:...|.:....:.:||::|.:..::|...||...|...:..  .:..||::|
Yeast   310 TASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMNDSFE--TSIVLGIVN 372

  Fly   318 FISALMGPWLMRSFNRRLMMTI-SCLCSAIFLVLLVVGLELM------STIHEFSFTC-IAFLSL 374
            |.|.....:.:....||..:.: :...:|..::...||:..:      ....:.:..| |.|...
Yeast   373 FASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTIVFTCF 437

  Fly   375 YIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATG---PFVFLL 436
            ||..|:...||..|.|.||.|....|...|::.:..|.|..|::....|.:.||..   .:||:.
Yeast   438 YIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIGFFTPFITSAINFYYGYVFMG 502

  Fly   437 CVVFCAYGFLLTYRYLPETRNRDAKDVAQLMENG 470
            |:   |:.:...:.::|||:....::|.::..:|
Yeast   503 CL---AFSYFYVFFFVPETKGLTLEEVDEMWMDG 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	111/469 (24%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	99/416 (24%)
HXT8	NP_012321.1	Sugar_tr	69..530	CDD:395036	114/483 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342919
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840