DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and HXT10

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_116644.1	Gene:	HXT10 / 850536	SGDID:	S000001883	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	507	Identity:	121/507 - (23%)
Similarity:	224/507 - (44%)	Gaps:	78/507 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRL---GDSQMTIIMS-T 68
            ||  ::.:|:.|..|     |:.||   ..:..|..:|.::..:|....|   |..|::.:.: .
Yeast    47 WT--VMGLCLMIAFG-----GFIFG---WDTGTISGFINQTDFKRRFGELQRDGSFQLSDVRTGL 101

  Fly    69 VVSIFLIGGMLGAPFAPIFSARLGRRGILTLSGLLLLVSCICQLF-----CRMANSIE--MLLLG 126
            :|.||.||..||       ...|||.|  .:.|..:.:.|:..::     .::|:|.:  ...:|
Yeast   102 IVGIFNIGCALG-------GLTLGRLG--DIYGRKIGLMCVILVYVVGIVIQIASSDKWYQYFIG 157

  Fly   127 RLIGGLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKL----- 186
            |::.|:....:....|..:.|::|..|.|:...|..:.:|.||.||...::    ||:|.
Yeast   158 RIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNY----GTKKYSNSIQ 218

  Fly   187 W--PYALSGS-AIFVLIGLAPIFWFPESPRFLMSQGRREKARVTLMRLRR----DEGRV---NAE 241
            |  |..|..: |||::||:..:   |||||:|:.:|:.|:||.:|.:..:    |.|.|   :..
Yeast   219 WRVPLGLCFAWAIFMVIGMVMV---PESPRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDTI 280

  Fly   242 MAEFEVSSTDEGQVTMKQVLCNSKLKLPLFIV-CSFHFVQQMSGISAIWFYSIEIFT----QSGF 301
            :|..|:... .|..:..::..|....||..|: .....:||::|.:..::|...||.    |..|
Yeast   281 VANMELERA-VGNASWHELFSNKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGMQDSF 344

  Fly   302 TAAVAMWLNFALGLLNFISALMGPWLMRSFNRRLMMTISCLCSAI-FLVLLVVGLELM------- 358
            ..::      .||.:||.|..:..:::..|.||..:.......|| |::...||:..:
Yeast   345 ETSI------VLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQGKDQ 403

  Fly   359 STIHEFSFTCIAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFP 423
            .:........|.|...:|.:|.:...|..|.|.:|.:....:..|||:....||:..|::....|
Yeast   404 PSSQSAGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTP 468

  Fly   424 TLNSATG---PFVFLLCVVFCAYGFLLTYRYLPETRNRDAKDVAQLMENGFK 472
            .:..:.|   .:||:.|::|   .:...:.::.||:....::|.::.|...|
Yeast   469 FITRSIGFSYGYVFMGCLIF---SYFYVFFFVCETKGLTLEEVNEMYEERIK 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	114/479 (24%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	102/423 (24%)
HXT10	NP_116644.1	Sugar_tr	52..512	CDD:395036	117/493 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342920
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840