Protein Alignment sut3 and SLC2A10

DIOPT Version :10

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 119/559 - (21%)
• Similarity: 198/559 - (35%)
• Gaps: 166/559 - (29%)

  Fly    15 ICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTIIMSTVVSIFLIGG-M 78
            :|..:::...:..||...|:                   |..|...|:...:|.:...||:|. :
Human    31 LCASVSLLGGLTFGYELAVI-------------------SGALLPLQLDFGLSCLEQEFLVGSLL 76

  Fly    79 LGAPFAPIFSARL----GRRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLIGGLAAALIYA 139
            |||..|.:....|    ||:..:..|.|:||..   .|...:|.|:..|:|||.:.|.|.:|...
Human    77 LGALLASLVGGFLIDCYGRKQAILGSNLVLLAG---SLTLGLAGSLAWLVLGRAVVGFAISLSSM 138

  Fly   140 TQPMYLVEL-APAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALS-GSAIFVLIGL 202
            ...:|:.|| .|.:....|.::.. |:|.||:|....:: .|.||...|.:... .:|..||..|
Human   139 ACCIYVSELVGPRQRGVLVSLYEA-GITVGILLSYALNY-ALAGTPWGWRHMFGWATAPAVLQSL 201

  Fly   203 APIFWFP------------------ESPRFLMSQGRREKARVTLMRLRRDEGRVNAEMAEFEVSS 249
            :.:| .|                  |:|:  :..||...:.:.|.| .||..|
Human   202 SLLF-LPAGTDETATHKDLIPLQGGEAPK--LGPGRPRYSFLDLFR-ARDNMR------------ 250

  Fly   250 TDEGQVTMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGF-TAAVAMWLNFAL 313
               |:.|:       .|.|.||        ||::|...:..|:..||:..|| ..:.|:..:..|
Human   251 ---GRTTV-------GLGLVLF--------QQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGL 297

  Fly   314 GLLNFISALMGPWLMRSFNRRLMMTISCL-----CSAIFLVLLVVGLE----------------- 356
            |.:...:.|....|:....||.::...|.     .|.|.||...|.::
Human   298 GAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGL 362

  Fly   357 -------------------------LMSTIHE--------------------------------- 363
                                     ::||..:
Human   363 PGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHA 427

  Fly   364 -FSFTCIAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNS 427
             ..:|.:..|.:::..|:.|.||..:.:.|||:....|..|.|..:.|||.||..:::.|..|..
Human   428 LLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIG 492

  Fly   428 ATG-PFVFLLCVVFCAYGFLLTYRYLPETRNRDAKDVAQ 465
            ..| .:.|||..:....|....|.::|||:.:...::.|
Human   493 TIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQ 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	MFS_GLUT_Class1_2_like	16..458	CDD:340915	118/549 (21%)
SLC2A10	XP_011527362.1	MFS_GLUT10_Class3	31..529	CDD:340994	118/555 (21%)