Protein Alignment sut3 and SLC2A5

DIOPT Version :10

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_003030.1
• Gene: SLC2A5 / 6518
• HGNCID: 11010
• Length: 501
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 128/471 - (27%)
• Similarity: 232/471 - (49%)
• Gaps: 9/471 - (1%)

  Fly     1 MADGKQGWTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTII 65
            |.:|:  .|.:|.|..:....|:....||....:|:|:..::.:..|:...|....:.|..:|::
Human     8 MKEGR--LTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLL 70

  Fly    66 MSTVVSIFLIGGMLGAPFAPIFSARLGRRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLIG 130
            .|..||:|..||.:|:........:.||:|.|..:.:..:|..|.....|:|.|.|::::.||:.
Human    71 WSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135

  Fly   131 GLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSA 195
            |:.|.:.....||||.||||..|.|::||...:.:|.||::.|:|....||.....||..|..:.
Human   136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTG 200

  Fly   196 IFVLIGLAPIFWFPESPRFLMSQGRREKARVTLMRLRRDEGRVNAEMAEFEVSSTDE-----GQV 255
            :...:.|..:.:||||||:|:.|.:.|.|....::..|....|:.|:|  |:...||     |.:
Human   201 VPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVA--EIRQEDEAEKAAGFI 263

  Fly   256 TMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLNFIS 320
            ::.::.....|:..|..:......||:||::||::|:.:|:..:|.......::....|.:|.:.
Human   264 SVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVM 328

  Fly   321 ALMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIHEFSFTCIAFLSLYIITFNMGLGP 385
            .....:::....|||::.:......|...:|...|.|..|:....:..|..:..|:|...:|..|
Human   329 TFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSP 393

  Fly   386 TPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPFVFLLCVVFCAYGFLLTYR 450
            .|..:.:|||..:|||||..:|...:||:||.:.:|||.:....||:.|::..|.|....:..:.
Human   394 IPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFL 458

  Fly   451 YLPETRNRDAKDVAQL 466
            .:|||:.:...::.|:
Human   459 IVPETKAKTFIEINQI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	MFS_GLUT_Class1_2_like	16..458	CDD:340915	122/446 (27%)
SLC2A5	NP_003030.1	MFS_GLUT_Class2	23..471	CDD:340990	122/449 (27%)