Protein Alignment sut3 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 140/498 - (28%)
• Similarity: 240/498 - (48%)
• Gaps: 50/498 - (10%)

  Fly     9 TCLLVLICVCITVGTVIPVGYAFGVMNAPSAF------------------IRSWIMESVLE---- 51
            |..||...:...:|: ...||..||:|||...                  |.::::.|..|
Human     7 TGTLVFTVITAVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTDELPTI 70

  Fly    52 RYS-----------SRLGDSQM-TIIMSTVVSIFLIGGMLGAPFAPIFSARLGRRGILTLSGLLL 104
            .||           ..:..:|: |::.|..||.|.:|||..:.|.......|||...:.::.:|.
Human    71 SYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILS 135

  Fly   105 LVSCICQLFCRMANSIEMLLLGRLIGGLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGI 169
            ||..:...|.::..|..:::.||.|.||...||....|||:.|:||..|.|::|.|..:.:..||
Human   136 LVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGI 200

  Fly   170 VLGQVFSFDFLLGTEKLWPYALSGSAIFVLIGLAPIFWFPESPRFLMSQGRRE-KARVTLMRLR- 232
            ::.|:...:|:||...||...|..|.:..::....:|:.|||||:|..:...| ||:.:|.|||
Human   201 LISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRG 265

  Fly   233 -----RDEGRVNAEMAEFEVSSTDEGQVTMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYS 292
                 :|...:..|..|    ::.|.:|::.|:..||..:.|:.:....|..||.|||:.|::||
Human   266 YDDVTKDINEMRKEREE----ASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYS 326

  Fly   293 IEIFTQSGFTAAVAMWLNFALGLLNFISALMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLEL 357
            ..||..:|.:..|  :....:|.:|.:...:..:|:....||.:..|......:..:.:.|||.|
Human   327 TSIFQTAGISKPV--YATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVL 389

  Fly   358 MSTIHEFSFTCIAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIF 422
            ::.....|:..:..:.|::..|.:|.||.|:|:.:|.|....||:|:|:.:|.||..||::.:.|
Human   390 LNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCF 454

  Fly   423 PTLNSATGPFVFLLCV-VFCAYGFLLTYRYLPETRNRDAKDVA 464
            ..:....||:||.|.. |..|: .|.|:..:|||:.:..:::|
Human   455 QYIADFCGPYVFFLFAGVLLAF-TLFTFFKVPETKGKSFEEIA 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	MFS_GLUT_Class1_2_like	16..458	CDD:340915	136/483 (28%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	136/485 (28%)