Protein Alignment sut3 and SLC2A1

DIOPT Version :10

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 137/448 - (30%)
• Similarity: 234/448 - (52%)
• Gaps: 9/448 - (2%)

  Fly    28 GYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTIIMSTVVSIFLIGGMLGAPFAPIFSARLG 92
            ||..||:|||...|..:..::.:.||...:..:.:|.:.|..|:||.:|||:|:....:|..|.|
Human    27 GYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFG 91

  Fly    93 RRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLIGGLAAALIYATQPMYLVELAPAELSGSV 157
            ||..:.:..||..||.:...|.::..|.|||:|||.|.|:...|.....|||:.|::|..|.|::
Human    92 RRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGAL 156

  Fly   158 GVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSAIFVLIGLAPIFWFPESPRFLMSQGRRE 222
            |....:|:..||::.|||..|.::|.:.|||..||...|..|:....:.:.|||||||:.....|
Human   157 GTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEE 221

  Fly   223 KARVTLMRLRRDEGRVNAEMAEFEVSSTD---EGQVTMKQVLCNSKLKLPLFIVCSFHFVQQMSG 284
            ....::::..|....|..::.|.:..|..   |.:||:.::..:...:.|:.|.......||:||
Human   222 NRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSG 286

  Fly   285 ISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLNFISALMGPWLMRSFNRRLMMTISCLCSAIFLV 349
            |:|:::||..||.::|....|  :.....|::|....::..:::....||.:..|.....|...:
Human   287 INAVFYYSTSIFEKAGVQQPV--YATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAI 349

  Fly   350 LLVVGLELMSTIHEFSFTCIAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLA 414
            |:.:.|.|:..:...|:..|..:..::..|.:|.||.|:||.:|:|....||:|:|:..|.||.:
Human   350 LMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTS 414

  Fly   415 NFVLNMIFPTLNSATGPFVFLLCVVFCAYGFLLTYRYLPETRNRDAKDVAQLMENGFK 472
            ||::.|.|..:....||:||::..|.....|:.||..:|||:.|...::|    :||:
Human   415 NFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA----SGFR 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	MFS_GLUT_Class1_2_like	16..458	CDD:340915	133/432 (31%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	133/432 (31%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		0/1 (0%)