Protein Alignment sut3 and SLC2A9

DIOPT Version :10

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_011512158.1
• Gene: SLC2A9 / 56606
• HGNCID: 13446
• Length: 615
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 124/472 - (26%)
• Similarity: 218/472 - (46%)
• Gaps: 31/472 - (6%)

  Fly     5 KQGWTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTIIMSTV 69
            ::.|:|.|::..:....|:....||...|:|||:.:|:::..||...|:...:....:|::.|..
Human    49 RKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVT 113

  Fly    70 VSIFLIGGMLGAPFAPIFSARLGRRGILTLS-----GLLLLVSCICQLFCRMANSIEMLLLGRLI 129
            ||||.|||::|.....:....|||:..|..:     ...||::|..|     |.:.|||::||.|
Human   114 VSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQ-----AGAFEMLIVGRFI 173

  Fly   130 GGLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGS 194
            .|:...:..:..||||.|::|.|:.||:|..|.|.:..|:..||:.....|||.|..|||.....
Human   174 MGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVI 238

  Fly   195 AIFVLIGLAPIFWFPESPRFLMSQGRREKARVTLMRLRRDEGRVNAEMAEFEVSSTDEGQVTMKQ 259
            .:..::.|..:.:.|:|||:|:.:...|...|...:....:..|:.|:.|....|..:..:.:..
Human   239 VVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVS 303

  Fly   260 VLCNSKLKLP----------LFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALG 314
            ||  ..|:.|          :.:.|     .|:.|::|||||:..||.::|...|...::..:.|
Human   304 VL--ELLRAPYVRWQVVTVIVTMAC-----YQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTG 361

  Fly   315 LLNFISALMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIHEFSFTCIAFLSLYIITF 379
            .:..::|:....::....||.::........:|...|.:.|.|........:..|..:...|.:|
Human   362 GIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASF 426

  Fly   380 NMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPFVFLLCVVFCAYG 444
            ..|.|..|:.:..|.|:.:.||:|..:....|||:||.:.::||.:..    .:.||.::....|
Human   427 CSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQL----LLLLLSLLRIQPG 487

  Fly   445 FLLTYRYLPETRNRDAK 461
            |.|.....|..:|...|
Human   488 FKLPPPPPPPKKNTHCK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	MFS_GLUT_Class1_2_like	16..458	CDD:340915	119/456 (26%)
SLC2A9	XP_011512158.1	MFS_GLUT_Class2	59..466	CDD:340990	111/418 (27%)