DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001178480.1	Gene:	Slc2a9 / 501925	RGDID:	1597012	Length:	545	Species:	Rattus norvegicus

Alignment Length:	493	Identity:	133/493 - (26%)
Similarity:	232/493 - (47%)	Gaps:	51/493 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GKQG--------WTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDS 60
            |::|        |:|.|::..:....|:....||...|:|||:.:|:::..|:...|:...:...
  Rat    28 GRRGWRPRRTKNWSCSLIVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNETWYRRHGQPIDPD 92

  Fly    61 QMTIIMSTVVSIFLIGGMLGAPFAPIFSARLGRRGILTLS-----GLLLLVSCICQLFCRMANSI 120
            .:|::.|..||||.|||::|.....:....|||:..|.::     ...||::|..|     |.:.
  Rat    93 TLTLLWSVTVSIFAIGGLVGTLMVKMIGKFLGRKYTLLVNNGFAISAALLMACSLQ-----AGTF 152

  Fly   121 EMLLLGRLIGGLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEK 185
            |||::||.|.|:...:..:..||||.|::|.|:.||:|..|.|.:..|:..||:.....|||.|:
  Rat   153 EMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLGKER 217

  Fly   186 LWPYALSGSAIFVLIGLAPIFWFPESPRFLMSQGRREKARVTLMRLRRDEGRVNAEMAEFEVSST 250
            .|||......:..|..||.:.:.|||||:|:.:             :.||.........| :...
  Rat   218 TWPYLFGVIIVPALAQLASLPFLPESPRYLLFE-------------KHDEAGATKAFQTF-LGKA 268

  Fly   251 DEGQVTMKQVLCNSKLKLPLFIVCSFHFVQ------------------QMSGISAIWFYSIEIFT 297
            |..| .:::.|..|:::..|.:|..|..::                  |:.|::|||||:..||.
  Rat   269 DVSQ-ELEEALAESRVQRNLRLVSVFELLRAPFVRWQVITVVITMASYQLCGLNAIWFYTNSIFG 332

  Fly   298 QSGFTAAVAMWLNFALGLLNFISALMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIH 362
            ::|.......::..:.|.:..::|:....::....||.::.......|:|..:|.|.|.|.....
  Rat   333 KAGVPQDKIPYITLSTGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGMLTVTLTLQDQAP 397

  Fly   363 EFSFTCIAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNS 427
            ...:..|..:...|.:|..|.|..|:.:..|.|:.:.||:|..:....|||:|||:.::||.:..
  Rat   398 WIPYLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFIIAGTVNWLSNFVVGLLFPFIQK 462

  Fly   428 ATGPFVFLLCVVFCAYGFLLTYRYLPETRNRDAKDVAQ 465
            :...:.||:....|..|.:..|..||||:||...:::|
  Rat   463 SLESYCFLVFATICIAGAIYFYFVLPETKNRTHAEISQ 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	127/461 (28%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	110/407 (27%)
Slc2a9	NP_001178480.1	Sugar_tr	47..502	CDD:278511	128/474 (27%)
Slc2a9	NP_001178480.1	MFS	49..486	CDD:119392	121/456 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338004
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	0.113	Inparanoid score	I2429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.800