DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and slc2a3a

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_005159482.1	Gene:	slc2a3a / 436916	ZFINID:	ZDB-GENE-040718-390	Length:	575	Species:	Danio rerio

Alignment Length:	510	Identity:	159/510 - (31%)
Similarity:	259/510 - (50%)	Gaps:	49/510 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADGKQGWTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTII 65
            |...|:..||.|:.......:|: :..||..||:|||...:|::...:.:|||...:.....||:
Zfish     1 MEGEKKQVTCYLLFSLSTAVIGS-LQFGYNTGVINAPEQKLRAFFNATWMERYGEPISPGVCTIV 64

  Fly    66 MSTVVSIFLIGGMLGAPFAPIFSARLGRRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLIG 130
            .|..|:||.:|||.|:....:.:.:.|||..:.|..:|.|:.......|.:.:|.||::.|||:.
Zfish    65 WSFAVAIFSVGGMAGSFSVGVVANKFGRRKSMILVNVLALIGGGLMGLCTLCSSFEMIIAGRLMI 129

  Fly   131 GLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSA 195
            ||...|.....|||:.|::|..|.|:.|....:|:..||::.|:|..:.|||::||||..|   |
Zfish   130 GLFCGLFTGLTPMYVGEVSPTPLRGAFGTLHQLGVVVGILIAQIFGLESLLGSDKLWPILL---A 191

  Fly   196 IFVLIGLAPIF---WFPESPRFLM-SQGRREKARVTLMRLR--RDEGRVNAEMAEFEVSSTDEGQ 254
            :.:|..:...|   :.|||||:|: :....|:||..|:|||  .|.|:...||.|.......|.:
Zfish   192 LTILPAILQCFLLPFCPESPRYLLINLNEEEQARKALVRLRGYEDVGKDMQEMKEESAKMAMEKK 256

  Fly   255 VTMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLNFI 319
            ||:.::..::..:.||||.......||:|||:|:::||..||..:|.|..:  :.....|::|.:
Zfish   257 VTIPELFRSAAYRQPLFIAIMLQLSQQLSGINAVFYYSTGIFKSAGVTQPI--YATIGAGVVNTV 319

  Fly   320 SALMGPWLMRSFNRRLM-------MTISCLCSAIFLVL-------------------LVVGLELM 358
            ..::..:|:....||.:       |.||.|...|.|:|                   |::.:.:.
Zfish   320 FTVVSLFLVERAGRRTLHLIGLGGMAISALAMTIALLLVRFTVCFNFVKILNQPQQYLMIMVNVF 384

  Fly   359 ST-------IHEFSFTCIAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANF 416
            .|       |....:..||.:..::..|.||.||.|:||.:|:|....||:|||:....||.|||
Zfish   385 ITFVSKQKDIEALQYLSIAAIFAFVAMFEMGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTANF 449

  Fly   417 VLNMIFPTLNSATGPFVFLLCVVFCAYGFLLTYRYLPETRNRDAKDVAQLMENGF 471
            ::.:.||.|....||:||::.::|....|:.||..:|||:.|...::|:    ||
Zfish   450 IVGITFPKLEELCGPYVFIIFMIFLIIFFIFTYFKVPETKGRTFDEIAR----GF 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	151/476 (32%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	133/423 (31%)
slc2a3a	XP_005159482.1	Sugar_tr	18..500	CDD:278511	152/491 (31%)
slc2a3a	XP_005159482.1	MFS	66..466	CDD:119392	127/404 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.800