DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_017175793.1	Gene:	Slc2a7 / 435818	MGIID:	3650865	Length:	553	Species:	Mus musculus

Alignment Length:	442	Identity:	132/442 - (29%)
Similarity:	238/442 - (53%)	Gaps:	18/442 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 IRSWIMESVLERYSSRLGDSQMTIIMSTVVSIFLIGGMLGAPFAPIFSARLGRRGILTLSGLLLL 105
            ::|:..::..||:.:.:.:|.:.::.|..||:|.:||:||:....:...:.||:|.|.::.:..:
Mouse    92 LKSFYNDTHFERHGTFMDESTLLLLWSCTVSMFPLGGLLGSLVVGLMVNKWGRKGTLLINNVFAI 156

  Fly   106 VSCICQLFCRMANSIEMLLLGRLIGGLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIV 170
            .|.:.....::|.:.|:::|.|::.|:.|.:.|:|.||||.||||..|.|::|..|.:.:..|::
Mouse   157 TSAVLMGVSKVARAFELIILSRVLVGICAGIAYSTLPMYLGELAPQNLRGALGTMTEVFVIIGVL 221

  Fly   171 LGQVFSFDFLLGTEKLWPYALSGSAIFVLIGLAPIFWFPESPRF-LMSQGRREKARVTLMRLRRD 234
            |.|:||...:||....||..|:.:.:..:|.|..:.:||||||: |:.:|..|.||..|.|||..
Mouse   222 LAQIFSLQAILGNATGWPILLALTGVPAVIQLLSLPFFPESPRYTLIEKGDEETARQALRRLRGQ 286

  Fly   235 EGRVNAEMAEF---EVSSTDEGQVTMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIF 296
            ...|.|||.|.   |.:...||::::..:.....|:..|..:......||:|||:|:.:|:..|:
Mouse   287 NYNVEAEMEEMRTEERTEQAEGRLSVLNLFTFRPLRWQLISIVVLMAGQQLSGINAVNYYADVIY 351

  Fly   297 TQSGFTAAVAMWLNFALGLLNFISALMGPWLMRSFNRRLMMT--ISCLCSAIFLVLLVVGLELMS 359
            |.:|.....:.::....|::|.:..|:...::....||:::.  .:..|||  .::|.|.|.|.|
Mouse   352 TSAGVDPTQSQYVTLGSGVINLVMTLVSAVIIERLGRRILLLSGYAICCSA--CLVLTVALLLQS 414

  Fly   360 TIHEFSFTCIAFLSLYIITFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPT 424
            |..|.|:..|..:..||:..::|..|.|..:.:||...:||.:|..:....:||.||::.:.||:
Mouse   415 TAPELSYLSIVCVFSYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFTVDGAVHWLTNFIVGLTFPS 479

  Fly   425 LNSATGPFVFL----LCVVFCAYGFLLTYRYLPETRNRDAKDV--AQLMENG 470
            :..|.|.:.||    :|::..||    .|..:|||:.|...::  |....||
Mouse   480 IQVAIGAYSFLVFAGVCILTAAY----IYVVIPETKGRTFVEINCAFAKRNG 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	130/436 (30%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	121/394 (31%)
Slc2a7	XP_017175793.1	MFS_GLUT_Class2	89..518	CDD:340990	129/431 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834183
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	320	1.000	Inparanoid score	I2506
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.760