Protein Alignment sut3 and SLC2A8

DIOPT Version :9

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_055395.2
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 477
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 116/482 - (24%)
• Similarity: 202/482 - (41%)
• Gaps: 88/482 - (18%)

  Fly    28 GYAFGVMN--APSAFIRSWIMESVLERY---SSRLGDSQMTIIMSTVVSIFLIGGMLGAPFAPIF 87
            |:|.|..:  .||           |:|.   :.||.|:..:...:.|......||:||.....
Human    41 GFALGYSSPAIPS-----------LQRAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVD-- 92

  Fly    88 SARLGRRGILTLSGLLLLVSCICQL-FCRMANSIEMLLLGRLIGGLAAALIYATQPMYLVELAPA 151
              |.||:    ||.||..|..:... ....|..:.|||.|||:.|||..:.....|:|:.|:|..
Human    93 --RAGRK----LSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYP 151

  Fly   152 ELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSAIFVLIGLAP-------IFWFP 209
            .:.|.:|  :|:.|.  :|:|.:.:  :|.|....|.:       ..::|..|       :.:.|
Human   152 AVRGLLG--SCVQLM--VVVGILLA--YLAGWVLEWRW-------LAVLGCVPPSLMLLLMCFMP 203

  Fly   210 ESPRFLMSQGRREKARVTLMRLRRDE-----GRVNAEMAEFEVSSTDEGQVTMKQVLCNSKLKLP 269
            |:||||::|.||::|...|..|...|     ..:.||.: |.::           :|....:..|
Human   204 ETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQS-FHLA-----------LLRQPGIYKP 256

  Fly   270 LFIVCSFHFVQQMSGISAIWFYSIEIFTQSGF-TAAVAMWLNFALGLLNFISALMGPWLMRSFNR 333
            ..|..|....||:||::|:.||:..||.::.| .:::|   :..:|::..:...:...:|....|
Human   257 FIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLA---SVVVGVIQVLFTAVAALIMDRAGR 318

  Fly   334 RLMMTISCLC---------------------SAIFLVLLVVGLELMSTIHEFSFTCIAFLSLYII 377
            ||::.:|.:.                     |:...:...|..:.:......::..:..:.|:|.
Human   319 RLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIA 383

  Fly   378 TFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPF-VFLLCVVFC 441
            .|.:|.||.|:.:.||||....:..|..:....|||..|::...|.:|.....|: .|.|...||
Human   384 GFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFC 448

  Fly   442 AYGFLLTYRYLPETRNRDAKDVAQLME 468
            .:..|.|...:|||:.:..:.:....|
Human   449 IFSVLFTLFCVPETKGKTLEQITAHFE 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	115/478 (24%)
		MFS	66..451	CDD:119392	102/420 (24%)
SLC2A8	NP_055395.2	Dileucine internalization motif. /evidence=ECO:0000250|UniProtKB:Q9JJZ1	12..13
		xylE	36..472	CDD:182225	115/477 (24%)
		MFS	38..459	CDD:119392	112/464 (24%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	267..273		4/5 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850