DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_006237357.1	Gene:	Slc2a3 / 25551	RGDID:	3706	Length:	495	Species:	Rattus norvegicus

Alignment Length:	477	Identity:	155/477 - (32%)
Similarity:	251/477 - (52%)	Gaps:	8/477 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADGKQGWTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTII 65
            |...||..|..||......|:|: ...||..||:|||...|:.::..::.||......:..:|.:
  Rat     1 MESNKQNVTPSLVFAVTVATIGS-FQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGLLTTL 64

  Fly    66 MSTVVSIFLIGGMLGAPFAPIFSARLGRRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLIG 130
            .|..|:||.:|||:|:....:|..|.|||..:.|..|:.::......|.::|.|:|||:|||||.
  Rat    65 WSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLII 129

  Fly   131 GLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSA 195
            |:...|.....|||:.|::|..|.|:.|....:|:..||::.|||..||:||:|:|||..|..:.
  Rat   130 GIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTI 194

  Fly   196 IFVLIGLAPIFWFPESPRFLMSQGRREKARVT--LMRL--RRDEGRVNAEMAEFEVSSTDEGQVT 256
            |..::..|.:.:.|||||||:. .|:|:.:.|  |.||  ..|..:...||.:..:..:.|.|||
  Rat   195 IPAILQSAALPFCPESPRFLLI-NRKEEDQATEILQRLWGTPDVIQEIQEMKDESIRMSQEKQVT 258

  Fly   257 MKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLNFISA 321
            :.::..:.....||.|.......||.|||:|:::||..||..:|....:  :.....|::|.|..
  Rat   259 VLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQEPI--YATIGAGVVNTIFT 321

  Fly   322 LMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIHEFSFTCIAFLSLYIITFNMGLGPT 386
            ::..:|:....||.:..|.....|:..|.:.:.|.|.......||.||..:.:|:..|.:|.||.
  Rat   322 VVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDEYEAMSFVCIVAILVYVAFFEIGPGPI 386

  Fly   387 PYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPFVFLLCVVFCAYGFLLTYRY 451
            |:||.:|:|....||:|||:....||.:||::.|.||:..:..|.:||::...|..:..:.|:..
  Rat   387 PWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVFFLIFTFFK 451

  Fly   452 LPETRNRDAKDVAQLMENGFKS 473
            :|||:.|..:|:.:..|...:|
  Rat   452 VPETKGRTFEDITRAFEGQAQS 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	145/441 (33%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	129/388 (33%)
Slc2a3	XP_006237357.1	Sugar_tr	15..467	CDD:278511	147/455 (32%)
Slc2a3	XP_006237357.1	MFS	16..450	CDD:119392	142/437 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	0.113	Inparanoid score	I2429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.800