DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and fgt-1

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_493982.1	Gene:	fgt-1 / 173525	WormBaseID:	WBGene00019207	Length:	510	Species:	Caenorhabditis elegans

Alignment Length:	468	Identity:	136/468 - (29%)
Similarity:	232/468 - (49%)	Gaps:	11/468 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DGKQGWTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTIIMS 67
            |||  .|..|......||:.: ...||..|.:|||...|..||:.|..:.:...|......:..|
Worm    39 DGK--LTKCLAFSAFVITLAS-FQFGYHIGCVNAPGGLITEWIIGSHKDLFDKELSRENADLAWS 100

  Fly    68 TVVSIFLIGGMLGAPFAPIFSARLGRRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLIGGL 132
            ..||:|.:|||:|...:...:.::||||.|..:.||.|.:.......:...:..|::|||||.||
Worm   101 VAVSVFAVGGMIGGLSSGWLADKVGRRGALFYNNLLALAAAALMGLAKSVGAYPMVILGRLIIGL 165

  Fly   133 AAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSAIF 197
            ......|..||:|.|::|..|.|.:|....:.:|..|::.|:|....||||...||...:.:.:.
Worm   166 NCGFSSALVPMFLTEISPNNLRGMLGSLHQLLVTIAILVSQIFGLPHLLGTGDRWPLIFAFTVVP 230

  Fly   198 VLIGLAPIFWFPESPRFLMS-QGRREKARVTLMRLRRDEGRVNAEMAEFEVSSTDEGQVTMKQV- 260
            .::.||.:...||||::.|: :|:|.:|...|.:| ||...|:.|:...:..:|..|.....::
Worm   231 AVLQLALLMLCPESPKYTMAVRGQRNEAESALKKL-RDTEDVSTEIEAMQEEATAAGVQEKPKMG 294

  Fly   261 -LCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLNFISALMG 324
             :....|..|:.|.......||:|||:...|||..||..:|.|.....:....:|.:|.|..|:.
Worm   295 DMFKGALLWPMSIAIMMMLAQQLSGINVAMFYSTVIFRGAGLTGNEPFYATIGMGAVNVIMTLIS 359

  Fly   325 PWLM--RSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIHE--FSFTCIAFLSLYIITFNMGLGP 385
            .||:  ..|.||.::........:..:|||..|.:.::..:  .|::.|.|:.|::|:|..|.|.
Worm   360 VWLVDHPKFGRRSLLLAGLTGMFVSTLLLVGALTIQNSGGDKWASYSAIGFVLLFVISFATGPGA 424

  Fly   386 TPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPFVFLLCVVFCAYGFLLTYR 450
            .|:|..||||::::|.:|.::....||.||.::.:.|..:|:....:.|.:...|.|:....|::
Worm   425 IPWFFVSEIFDSSARGNANSIAVMVNWAANLLVGLTFLPINNLMQQYSFFIFSGFLAFFIFYTWK 489

  Fly   451 YLPETRNRDAKDV 463
            ::|||:.:..:.:
Worm   490 FVPETKGKSIEQI 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	129/443 (29%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	115/391 (29%)
fgt-1	NP_493982.1	Sugar_tr	50..506	CDD:278511	131/455 (29%)
fgt-1	NP_493982.1	MFS	100..491	CDD:119392	115/391 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I2266
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28646
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.910