DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and Slc2a13

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_598295.2	Gene:	Slc2a13 / 171147	RGDID:	621814	Length:	637	Species:	Rattus norvegicus

Alignment Length:	545	Identity:	132/545 - (24%)
Similarity:	207/545 - (37%)	Gaps:	132/545 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTIIMSTVVSIFLIGGMLGAPFAPIFSARLG 92
            ||..||::.          ..:|.|...|||.....:::|..|....:..:.|.    ..:..||
  Rat    85 GYDTGVVSG----------AMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGG----ALNGALG 135

  Fly    93 RRGILTLSGLLLLVSCIC----QLFCRMANSIEMLLLGRLIGGLAAALIYATQPMYLVELAPAEL 153
            ||      ..:||.|.:|    .:....||. |.||.|||:.||...:...|.|:|:.|::|..|
  Rat   136 RR------SAILLASALCTVGSAVLAAAANK-ETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNL 193

  Fly   154 SGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSAIFVLIGLAPIFWFPESPRFLMSQ 218
            .|.:.....:.:|||.....|....|....:..|.|.|..:||..:|......:.|||||:|:.:
  Rat   194 RGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQK 258

  Fly   219 GRREKARVTLMRLR--------RDEGRVNAEMAEFEVSSTDEGQVTMKQVLCNSKLKLP-----L 270
            |:.:|||..|.::|        .|..|.:.|..|.|.|:..       .::|. .|..|     |
  Rat   259 GQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEEKEASAAG-------PIICR-MLSYPPTRRAL 315

  Fly   271 FIVCSFHFVQQMSGISAIWFYSIEIFTQSGF-TAAVAMWLNFALGLLNFISALMGPWLMRSFNRR 334
            .:.|.....||:|||:.|.:||..|...||. ...:|:||.......|||..|:|.||:....||
  Rat   316 AVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRR 380

  Fly   335 LMMTISCLCSAIFLVLLVVGLELMSTIH------------------------------------- 362
            .:...|...:.:.|.:|.:|..|.:.:.
  Rat   381 KLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYK 445

  Fly   363 -----------------------------------------------EFSFTCIAFLSLYIITFN 380
                                                           .:|:|.:..|.||::.|.
  Rat   446 INSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGLVLYLVFFA 510

  Fly   381 MGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIF-PTLNSATGPFVFLLCVVFCAYG 444
            .|:||.|:.:.|||:...:|.:..|..:..||:.|.::::.| .|....|....|.|...|.|.|
  Rat   511 PGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVG 575

  Fly   445 FLLTYRYLPETRNRDAKDVAQLMEN 469
            .|..|..||||:.:..:::..|.::
  Rat   576 LLFVYGCLPETKGKKLEEIESLFDH 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	131/540 (24%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	118/487 (24%)
Slc2a13	NP_598295.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..38
		MFS	75..580	CDD:119392	126/523 (24%)
		Sugar_tr	78..598	CDD:278511	131/541 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930