DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001095884.1	Gene:	Slc2a9 / 117591	MGIID:	2152844	Length:	538	Species:	Mus musculus

Alignment Length:	473	Identity:	129/473 - (27%)
Similarity:	222/473 - (46%)	Gaps:	27/473 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMTIIMSTVVSI 72
            |:..||:..:....|:....||...|:|||:.:|:::...:...|:...:....:|::.|..|||
Mouse    33 WSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGTWYRRHGQPIDPDTLTLLWSVTVSI 97

  Fly    73 FLIGGMLGAPFAPIFSARLGRRGIL------TLSGLLLLVSCICQLFCRMANSIEMLLLGRLIGG 131
            |.|||::|.....:....|||:..|      .:|..||:.   |.|   .|.:.|||::||.|.|
Mouse    98 FAIGGLVGTLMVKMIGKFLGRKSTLLVNNGFAISAALLMA---CSL---RAGTFEMLIVGRFIMG 156

  Fly   132 LAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALSGSAI 196
            :...:..:..||||.|::|.|:.||:|..|.|.:..|:..||:.....|||.|..|||......:
Mouse   157 VDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLGRESTWPYLFGVIIV 221

  Fly   197 FVLIGLAPIFWFPESPRFLMSQGRREKARVTLMRLRRDEGRVNAEMAEFEVSSTDEGQVTMKQVL 261
            ..|:.||.:.:.|||||:|:.:...|...:...:....:..|:.|:.|....|..:..:.:..||
Mouse   222 PALVQLASLPFLPESPRYLLFEKHDEAGAMKAFQTFLGKADVSQELEEALAESRVQRNLRLVSVL 286

  Fly   262 CNSKLKLP---------LFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLN 317
              ..|:.|         :..:.|:    |:.|::|||||:..||.::|.......::..:.|.:.
Mouse   287 --ELLRAPFVRWQVITVIITMASY----QLCGLNAIWFYTNSIFGKAGIPQDKIPYITLSTGGIE 345

  Fly   318 FISALMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIHEFSFTCIAFLSLYIITFNMG 382
            .::|:....::....||.::.......|:|...|...|.|........:..|..:...|.:|..|
Mouse   346 TLAAIFSGLVIERLGRRPLLIGGFGLMALFFGTLTATLTLQDQAPWVPYLSIVCILAIIASFCSG 410

  Fly   383 LGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPFVFLLCVVFCAYGFLL 447
            .|..|:.:..|.|:.:.||:|..:....|||:||.:.::||.:..:...:.||:....|..|...
Mouse   411 PGGIPFILTGEFFQQSERPAAFMIAGTVNWLSNFAVGLLFPFIQKSLDSYCFLVFATICIAGATY 475

  Fly   448 TYRYLPETRNRDAKDVAQ 465
            .|..||||:||...:::|
Mouse   476 FYFVLPETKNRTHAEISQ 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	125/453 (28%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	109/399 (27%)
Slc2a9	NP_001095884.1	MFS_GLUT_Class2	40..491	CDD:340990	125/462 (27%)
Slc2a9	NP_001095884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..538
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834435
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	320	1.000	Inparanoid score	I2506
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.800