Protein Alignment sut3 and SLC2A6

DIOPT Version :9

• Sequence 1: NP_524731.1
• Gene: sut3 / 44268
• FlyBaseID: FBgn0028561
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_060055.2
• Gene: SLC2A6 / 11182
• HGNCID: 11011
• Length: 507
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 112/461 - (24%)
• Similarity: 191/461 - (41%)
• Gaps: 94/461 - (20%)

  Fly    71 SIFLIGGMLGAPFAPIFSARLGRR------GILTLSGLLLLVSCICQLFCRMANSIEMLLLGRLI 129
            |:|.:|...|...|.|.:..|||:      .:.:.:|..|:..         |:.:.||||||.:
Human    86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---------AHGLWMLLLGRTL 141

  Fly   130 GGLAAALIYATQPMYLVELAPAELSGSVG-------VFTCIGLTGGIVLGQVFSFDFLLGTEKLW 187
            .|.|..|..|..|:|:.|:||..:.|::|       ||..:.|             :.||....|
Human   142 TGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSL-------------YALGLLLPW 193

  Fly   188 PY-ALSGSAIFVLIGLAPIFWFPESPRFLMSQGRREKARVTLMRLRRDEGRVNAEMAEFEVS-ST 250
            .: |::|.|. |||.:..:.:.|.|||||:|:||.|:|...|..||..:..|:.|..:.:.: ..
Human   194 RWLAVAGEAP-VLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRR 257

  Fly   251 DEGQVTMKQV----LCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGF------TAAV 305
            ...:|:..:.    :|.     |:.:......:||::||:.|..|...||..:..      .||:
Human   258 QSSRVSWAEARAPHVCR-----PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI 317

  Fly   306 AMWLNFALGLLNFISALMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIHEFS----- 365
                   :|.:..:|.|:....|....|::::.:|  .:.:|...|.:||.:.......|
Human   318 -------VGAVRLLSVLIAALTMDLAGRKVLLFVS--AAIMFAANLTLGLYIHFGPRPLSPNSTA 373

  Fly   366 --------------------FTCIAFLS--LYIITFNMGLGPTPYFIGSEIFETASRPSAMALGS 408
                                .|.:..|:  |:|:.:.:|.||..:.:.||:....:|..|..|..
Human   374 GLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCV 438

  Fly   409 FFNWLANFVLNMIFPTLNSATG---PFVFLLCVVFCAYGFLLTYRYLPETRNRDAKDVAQLMENG 470
            ..:||..|||...|..:.|..|   ||.|...:  |....:.|...:|||:.|..:.:......|
Human   439 LASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAI--CLVSLVFTGCCVPETKGRSLEQIESFFRTG 501

  Fly   471 FKSKIK 476
            .:|.::
Human   502 RRSFLR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	110/449 (24%)
		MFS	66..451	CDD:119392	106/434 (24%)
SLC2A6	NP_060055.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS_GLUT6_Class3	39..493	CDD:340992	110/445 (25%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	286..292		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850