DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and slc2a4

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_031755513.1	Gene:	slc2a4 / 101731550	XenbaseID:	XB-GENE-5943313	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	480	Identity:	144/480 - (30%)
Similarity:	241/480 - (50%)	Gaps:	37/480 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KQGWTCLLVLICVCITVGTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSS---RLGDSQMTIIM 66
            :.|.|..|||......:|: ...||..||:|||...|.....||.:.|.||   .:....:..:.
Frog    17 RSGVTKTLVLSVFTAILGS-FQFGYNIGVINAPQKIIEQSYNESWISRSSSGSASIDPGLLRTLW 80

  Fly    67 STVVSIFLIGGMLGAPFAPIFSARLGRRGILT-------LSGLLLLVSCICQLFCRMANSIEMLL 124
            |..|:||.||||:.:....:.|..|||:..:.       |:|..:.:|.:||       |.||::
Frog    81 SLSVAIFSIGGMVSSLSVGVVSQWLGRKRAMVINNVFAFLAGSFMGLSQVCQ-------SYEMMI 138

  Fly   125 LGR-LIG---GLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEK 185
            :|| |||   |||:.|:    |||:.|::|..|.|::|....:.|..||::.||...:..|||..
Frog   139 VGRFLIGVYSGLASGLV----PMYVGEISPTHLRGAMGTLHQLSLVIGILVAQVLGLELFLGTNT 199

  Fly   186 LWPYALSGSAIFVLIGLAPIFWFPESPRFLMSQGRRE-KARVTLMRLR--RDEGRVNAEMAEFEV 247
            .||.....:.|...:....:.:.|||||||.....:| :|:.:|.||.  .|.....::|.|.:.
Frog   200 RWPALFWVTLIPAALQCLMLPFCPESPRFLYIVCEQEAQAKKSLRRLTGLPDVTDDLSDMKEEKR 264

  Fly   248 SSTDEGQVTMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFA 312
            ....|.:|::.|:..:...:.|:.:.......||:|||:||::||.:||:::|....:  :....
Frog   265 QMDSEPKVSILQIFRSRNYRQPILVAIVLQLSQQLSGINAIFYYSTDIFSKAGVEQPI--YATIG 327

  Fly   313 LGLLNFISALMGPWLMRSFNRRLMMTISCLCSAIFLVLLVVGLELMSTIHEFSFTCIAFLSLYII 377
            .|::|....::..:|:....||.:..:......:..:|:...:.|..::...|:..:|.:..::.
Frog   328 AGIVNTAFTVVSLFLVERAGRRTLQLLGLAGMIVCALLMTAAMVLQESVPSLSYLSMAAIFGFVA 392

  Fly   378 TFNMGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPFVFLLCVVFCA 442
            .|.:|.||.|:||.:|:|....||:|||:....||.:||::.|.|..:....||:||||   |.|
Frog   393 FFEIGPGPIPWFIVAELFSQGPRPAAMAIAGCTNWTSNFIIGMGFQYVAELCGPYVFLL---FGA 454

  Fly   443 --YGFLL-TYRYLPETRNRDAKDVA 464
              :.||: ||..:||||.|...:::
Frog   455 LLFAFLIFTYFRVPETRGRSFDEIS 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	138/457 (30%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	120/401 (30%)
slc2a4	XP_031755513.1	MFS_GLUT_Class1	26..473	CDD:340989	139/463 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2586
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060