DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut3 and slc2a5

DIOPT Version :9

Sequence 1:	NP_524731.1	Gene:	sut3 / 44268	FlyBaseID:	FBgn0028561	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001352581.1	Gene:	slc2a5 / 100006415	ZFINID:	ZDB-GENE-060222-2	Length:	511	Species:	Danio rerio

Alignment Length:	485	Identity:	135/485 - (27%)
Similarity:	249/485 - (51%)	Gaps:	16/485 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADGKQGWTCLLVLICVCITV--GTVIPVGYAFGVMNAPSAFIRSWIMESVLERYSSRLGDSQMT 63
            |..|::.....|:|....:..  |:....||...|:|:|:..::.:.....::||.. :.|:.:|
Zfish     7 MKKGERKGKVTLILAAASLVAGFGSSFQYGYNVAVVNSPAPEMQQFYRRIYVDRYGP-MSDNLLT 70

  Fly    64 IIMSTVVSIFLIGGMLGA-PFAPIFSARLGRRGILTLSGLLLLVSCICQLFCRMANSIEMLLLGR 127
            ::.|..||::.:||..|: ..||:.: :.||:|.|..:.:..:|..|......:|.|.|::::.|
Zfish    71 LLWSVTVSMYPLGGFFGSLMVAPLVN-KFGRKGTLLFNNIFSIVPAIMMGVSEVAGSFEIIIVAR 134

  Fly   128 LIGGLAAALIYATQPMYLVELAPAELSGSVGVFTCIGLTGGIVLGQVFSFDFLLGTEKLWPYALS 192
            .:.|:.|.|.....||||.|:||....|:||:...:.:|.||::.|:|....:||.::.||..|.
Zfish   135 FLVGICAGLSSNVVPMYLGEIAPKNYRGAVGIVPQLFITVGILVAQIFGIRSILGNKEGWPIMLG 199

  Fly   193 GSAIFVLIGLAPIFWFPESPRFLMSQ-GRREKARVTLMRLRRDEGRVNAEMAEFEV---SSTDEG 253
            .:.|...|.|..:.:||||||:::.| |..:.||..|.|||..|. |:.|:.|..|   |...||
Zfish   200 LTGIPAAIELLLLPFFPESPRYMLIQKGDEKTARKGLQRLRGCED-VDEELCEMRVEEQSERAEG 263

  Fly   254 QVTMKQVLCNSKLKLPLFIVCSFHFVQQMSGISAIWFYSIEIFTQSGFTAAVAMWLNFALGLLNF 318
            ::::..:.....|:..|..|...:..||:||::||::|:..|::.:|.:.....::....|.:|.
Zfish   264 RLSLLNLFTFRSLRWQLLSVIFMNMGQQLSGVNAIYYYADSIYSSAGVSEDHVQYVTVGTGAVNV 328

  Fly   319 ISALMGPWLMRSFNRRLMMTIS---CLCSAIFLVLLVVGLELMSTIHEFSFTCIAFLSLYIITFN 380
            ...:...:::....|:|::.|.   | |:|  .|:|.:.|...:|:....:..|..:.:|:|...
Zfish   329 FMTITAVFIVEKSGRKLLLLIGFGIC-CAA--CVILTIALYFQTTLDWIPYVSIVCVIVYVIGHA 390

  Fly   381 MGLGPTPYFIGSEIFETASRPSAMALGSFFNWLANFVLNMIFPTLNSATGPFVFLLCVVFCAYGF 445
            :|..|.|..|.:|:|..:|||.|..:....:||:||.:.::||.|....||:.|::....|....
Zfish   391 IGPSPIPTVITTEMFRQSSRPPAFMVAGSVHWLSNFTVGLVFPFLERGLGPYSFIIFACICLATL 455

  Fly   446 LLTYRYLPETRNRDAKDVAQLMENGFKSKI 475
            :..:..:|||:|:...:.::|.....|.:|
Zfish   456 IYIWIVIPETKNKTFLETSKLFAQRNKVEI 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut3	NP_524731.1	Sugar_tr	28..466	CDD:278511	127/445 (29%)
sut3	NP_524731.1	MFS	66..451	CDD:119392	114/392 (29%)
slc2a5	NP_001352581.1	Sugar_tr	23..477	CDD:306568	128/459 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.960