Protein Alignment Sara and CG6051

DIOPT Version :10

• Sequence 1: NP_524729.2
• Gene: Sara / 44263
• FlyBaseID: FBgn0026369
• Length: 1343
• Species: Drosophila melanogaster
• Sequence 2: NP_001097943.1
• Gene: CG6051 / 43271
• FlyBaseID: FBgn0039492
• Length: 989
• Species: Drosophila melanogaster
• Alignment Length: 698
• Identity: 147/698 - (21%)
• Similarity: 249/698 - (35%)
• Gaps: 171/698 - (24%)

  Fly     6 IDQVLDNLELSIAADEQLSRNAAAAAAAGANPGRFLGDGASASISGVGAGAGVSGAAGVTPTPAS 70
            :::::|....:..::...|.|....||...:|            |.:...|..:..|...|:|..
  Fly   365 VERLVDQRNNNHNSNSNSSTNPTVEAATLRSP------------SMLSLSATSTPTASPAPSPTP 417

  Fly    71 GKSFVGVSQVFNSL----------DDYRENVKSLQVDAQ-LPSYDWQTEAEH------------- 111
            ..|....|....|.          ||..|:...:.||.: :.|.|..|:.|.
  Fly   418 SHSIASTSSAATSSTNPPADWSDGDDEDEDDDDIDVDEEDIESSDDGTDEEQLLKDIVSADCASG 482

  Fly   112 --------------------------EDDIHKFSEQASKNNGQTIVSSSESLTTSSCSTFSSGPS 150
                                      |||.:..:||......:....|:.:...::..|......
  Fly   483 YLIPNTNLGNLLQPQEVPLTDNFVASEDDEYGTAEQQGHQGLEEDEPSTSAAMLAATRTLQRLRL 547

  Fly   151 PVSNGSHSEELATPPEDEKTSEVQVEPK------------EQDQQPEQVKHEDQHQDQAVPPPTQ 203
            |   .|.:|.||.|...:.:.|...:|.            ::.......:|..|||.:. |.|.:
  Fly   548 P---SSDNEPLAEPTTIKASEEHMQQPSGRHRDSHSHRHHQRHHHHHHHRHPHQHQHRQ-PHPHR 608

  Fly   204 SKQTVEELAVGLSSISITASGTE------SQSLLPEEVTASSVLGQVLEELSEESSPSR---EPE 259
            :.::      |....|:.|:..|      .|:|...:.:|:|.|...: .|:..::.:|   :..
  Fly   609 TTRS------GRKRCSLEAADPERIQPDREQNLASGDTSAASSLSDDV-SLAMRNTTARLKFKST 666

  Fly   260 TEMTNGIDVPLANLPASVAEVPVPKEMEQ--------PVQTEEEDVELPQEQHPRRSQPLTFCST 316
            ..:.:.:.|.:|.: |...:.....::.|        .:.|.:|::::|::..
  Fly   667 ENLLHRLFVCIAGV-ADQLQTNFASDLRQILRSVFLMNMSTAQEEIDIPEKTK------------ 718

  Fly   317 MDEISDTELDSMLQEMDADDNQADDQQMPDDEKSCSASPVTEE-ESVRILSDEQETTSNDQMNVD 380
                     :|.|.|..|.:|....:....::...||..|..| ::|.......:.|........
  Fly   719 ---------ESELFEFRASENDVIQESAGSNQSIYSAEEVNPELDNVFSAGGGNQATGQRHSAGA 774

  Fly   381 NFSQASTVEFADLKQP-ESTPVTAMGEDVASSFSS-TESDSLSGRKLDGEVEVDREHEDASLATD 443
            :..:.:|::.|  .|| |.:|   .|...|:|.|. |.|.||.            :.|.||.||.
  Fly   775 SMQRNNTIDLA--SQPGEGSP---SGATTATSRSHVTRSRSLG------------DQEAASSATS 822

  Fly   444 A------LETQEQRPQ-----RPQTLNLNGCQAESSTPSQDENPEIQQETLQPTEVREGAAGVGV 497
            :      ||.|:|:.|     :.|..|..|    |:|||...:.....|...|...|.|:.  ..
  Fly   823 STAQLRQLEQQQQQQQLQIQLQRQRNNSVG----SNTPSSASSTSSSSEQNSPVSARSGSR--RR 881

  Fly   498 IPGEDDEESPIYEAVGYSDPHANLGKVPPIWVPDNMAGQCMQCQQKFTMIKRRHHCRACGKVLCS 562
            :...::.:.|    ...:...|.|.  ||.|:||..|.:||.||..||..:||||||.||.|.|.
  Fly   882 LQSNNETQMP----SSATSTSATLS--PPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCG 940

  Fly   563 VCCSQRFRL-EFATEPESRVCVQCYM--ILSERQANGLNS-ESAPGSA 606
            ||.:....| ::......|||..||:  :.|.....|:.| :|...||
  Fly   941 VCSNASAPLPKYGLTKAVRVCRDCYVREVRSGMGVQGVQSVQSVQASA 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sara	NP_524729.2	FYVE_endofin	522..589	CDD:277268	30/69 (43%)
		SARA	614..650	CDD:463271
		DUF3480	959..1321	CDD:463419
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	29/65 (45%)