Protein Alignment eIF5B and eEF1alpha2

DIOPT Version :10

• Sequence 1: NP_651974.1
• Gene: eIF5B / 44261
• FlyBaseID: FBgn0026259
• Length: 1144
• Species: Drosophila melanogaster
• Sequence 2: NP_524611.1
• Gene: eEF1alpha2 / 43736
• FlyBaseID: FBgn0000557
• Length: 462
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 97/518 - (18%)
• Similarity: 161/518 - (31%)
• Gaps: 214/518 - (41%)

  Fly   558 VCVLGHVDTGKTK------------------------------------ILDKLRRTHVQDSEAG 586
            :.|:||||:||:.                                    :||||:....:
  Fly    10 IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERER----- 69

  Fly   587 GITQQIGATNVPIEAIKEQTKYVKAAAGFEHRLPGLLIIDTPGHESFSNLRNRGSSLCDIAILVV 651
            |||..|.....      |.:||.            :.|||.|||..|......|:|..|.|:|:|
  Fly    70 GITIDIALWKF------ETSKYY------------VTIIDAPGHRDFIKNMITGTSQADCAVLIV 116

  Fly   652 -----DIMHGLEP--QTIESIQL---LKKKKCPFIVALNKIDRLYDWKQLARRDVRDVLKEQQSN 706
                 :...|:..  ||.|...|   |..|:  .||.:||:|                 ..:...
  Fly   117 AAGTGEFEAGISKNGQTREHALLAFTLGVKQ--LIVGVNKMD-----------------STEPPY 162

  Fly   707 TQLEFQQRTKDVILQFAEQGLNAALFYENTDPKTYISLVPTSAISGEGM---------------- 755
            ::..:::..|:|.....:.|.|.|          .::.||.|...|:.|
  Fly   163 SEARYEEIKKEVSSYIKKIGYNPA----------SVAFVPISGWHGDNMLEPSEKMPWFKGWSVE 217

  Fly   756 -------GNLLFMIADFCQNMLAKRLMYSEELQATVLEVKALPGLGTTIDAILINGKLREGQTMV 813
                   |..|.   |....:|..:....:.|:..:.:|..:.|:||.....:..|.|:.|  ||
  Fly   218 RKEGKAEGKCLI---DALDAILPPQRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGLLKPG--MV 277

  Fly   814 VAGTDGPIVTQIRSLLMPQ-------------------PMKELR--------------------- 838
            |......:||:::|:.|..                   .:||||
  Fly   278 VNFAPVNLVTEVKSVEMHHEALTEAMPGDNVGFNVKNVSVKELRRGYVAGDSKNNPPRGAADFTA 342

  Fly   839 ----------VKNAYV------------EYKEVK------AAQGVKIAAKDLEKAIAGINLLIAH 875
                      :.|.|.            ::.|:|      ..:..:...|.::...|.|.:|:..
  Fly   343 QVIVLNHPGQIANGYTPVLDCHTAHIACKFSEIKEKCDRRTGKTTETEPKAIKSGDAAIIVLVPS 407

  Fly   876 KPDEVEICTEE----------VARELKS--ALSHIKLAQTGVHVQASTLGSLEALLEFLRTSK 926
            ||    :|.|.          ..|:::.  |:..||    .|:.:.:|.|.:....|..:..|
  Fly   408 KP----LCVESFQEFPPLGRFAVRDMRQTVAVGVIK----SVNFKETTSGKVTKAAEKAQKKK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF5B	NP_651974.1	PRK04004	553..1129	CDD:457675	97/518 (19%)
eEF1alpha2	NP_524611.1	PTZ00141	1..450	CDD:185474	94/504 (19%)