Protein Alignment eIF5B and CG2017

DIOPT Version :9

• Sequence 1: NP_001246599.1
• Gene: eIF5B / 44261
• FlyBaseID: FBgn0026259
• Length: 1144
• Species: Drosophila melanogaster
• Sequence 2: NP_649603.3
• Gene: CG2017 / 40733
• FlyBaseID: FBgn0037391
• Length: 643
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 93/510 - (18%)
• Similarity: 170/510 - (33%)
• Gaps: 124/510 - (24%)

  Fly   380 ARAQALLESLKAQGLEIPDPNDKRPTRPGTRIRPNKKKGPKEEAAEEEAK---------AAEAEA 435
            :..|.::||.    |.:.|||                   :::..|||.:         ::.::.
  Fly    34 SNCQHIMESF----LSLFDPN-------------------QDDGFEEEPELNGNSSGGGSSSSDY 75

  Fly   436 QSAAAAAAAAAAEKAEEERVKESWDATDSEAEPEPE----EETSQATN----------------- 479
            ::.|.|...:.......||....:|.......|||:    |...:..|
  Fly    76 ETDANANECSVVSGMPTERGNLIFDFEQGMLPPEPQLGNVEYKLKLVNPSKQRFEHLVTQMKWRL 140

  Fly   480 -NGKTEAAEEENEDTDDDEDDDDDEDDSDDSDGDSDDSREVSVLANDPESRRLRAEARILKRQAE 543
             .|..||..|..            ..|:....|.||.....|:......:..|.|...:|:|:..
  Fly   141 REGNGEAIYEIG------------VSDAGYLQGLSDKDMNASLTTLKQMAHSLGASTSVLRRKTI 193

  Fly   544 AEKKRSTDELRAGV----------VCVLGHVDTGKTKILDKLRR---------------THVQDS 583
            |.::...:.|...:          |.|||..|.||:.:|..|.:               .|:.:.
  Fly   194 AARRAVAEVLVRKIPDDQHNIEVRVAVLGGADAGKSTLLGVLTQDELDNGHGRARLNMFRHMHEI 258

  Fly   584 EAGGITQQIGATNVPIEAIKEQTKY----VKAAAGFEHRLPGLL-IIDTPGHESFSNLRNRGSSL 643
            ::|. |..|....:..:|:.....|    :..|.....|...|: .:|..||..:  :|....:|
  Fly   259 QSGR-TSCISHETLGFDALGNVVNYKYNEMMTAEEISDRSSKLVTFMDLAGHRRY--MRTTVQAL 320

  Fly   644 C----DIAILVVDIMHGLEPQTIESIQLLKKKKCPFIVALNKIDRLYDWKQLARRDVRDVLKEQQ 704
            .    ..|:|||....|....|.|.:.:::....||.|.:.|.|....          |...::.
  Fly   321 SGYSPHYAMLVVSAGSGCNDTTEEHLAIVRALDMPFFVLVTKTDITSP----------DATVQEL 375

  Fly   705 SNTQLEFQQRTKDVILQFAEQGLNAALFYENTDPKTYISLVPTSAISGEGMG---NLLFMIADFC 766
            .|.......|....::...::.::|.   .|...:..:.:...|.::|.|:.   ..|::::...
  Fly   376 CNLLTTIGCRKVPFVVTNTDEAISAG---SNQISENIVPIFCVSNVTGTGLNLVTKFLYVLSPGI 437

  Fly   767 QNMLAKRLMYSEELQATVLEVKALPGLGTTIDAILINGKLREGQTMVVAGTDGPI 821
            .|....|| ..|..:..|.|:..:..:|..:..:|:.|.|.|...|.:    ||:
  Fly   438 SNAEKDRL-EQESCEFQVDEIFRVSDVGPVVGGLLVQGVLTENMAMKI----GPL 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF5B	NP_001246599.1	PRK04004	553..1129	CDD:235195	59/306 (19%)
		IF2_eIF5B	557..769	CDD:206674	44/248 (18%)
		aeIF5B_II	779..889	CDD:293904	10/43 (23%)
		IF-2	890..993	CDD:288813
		IF2_aeIF5B_IV	1016..1110	CDD:293911
CG2017	NP_649603.3	GTPBP1	100..635	CDD:227583	79/421 (19%)
		GTPBP1_like	217..436	CDD:206728	44/234 (19%)
		GTPBP_II	450..536	CDD:293895	10/42 (24%)
		GTPBP_III	547..634	CDD:294007

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930