Protein Alignment eIF5B and eEFSec

DIOPT Version :9

• Sequence 1: NP_001246599.1
• Gene: eIF5B / 44261
• FlyBaseID: FBgn0026259
• Length: 1144
• Species: Drosophila melanogaster
• Sequence 2: NP_611584.1
• Gene: eEFSec / 37444
• FlyBaseID: FBgn0034627
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 112/552 - (20%)
• Similarity: 187/552 - (33%)
• Gaps: 196/552 - (35%)

  Fly   560 VLGHVDTGKT---KILDKLRRTHVQD----SEAGGITQQIGATNVPIEAIK-----EQTKYVKAA 612
            :|||||:|||   |.|..:..|...|    |...|||..:|.:.:.::|..     ||.::.
  Fly     9 LLGHVDSGKTTLAKALSSISSTAAFDKNPQSVERGITLDLGFSGLLVDAPAHLPQGEQLQFT--- 70

  Fly   613 AGFEHRLPGLLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESI---QLLKKKKCP 674
                       .:|.|||.|.......|:.:.|:.:||||...|.:.||.|.:   :||:||
  Fly    71 -----------FVDCPGHASLIRTIIGGAQIIDLMLLVVDAQKGKQTQTAECLIIGELLQKK--- 121

  Fly   675 FIVALNKIDRLYDWKQLARRDVRDVLKEQQSNTQLEFQQRTKDVILQFAEQGLNAALFYENTDPK 739
            .||.:|||               ||..|.|..::||             :..|..|...|.|...
  Fly   122 LIVVINKI---------------DVYPENQRASKLE-------------KLRLRLAKTLEATTFG 158

  Fly   740 TYISLVPTSAISGEGMGNL------------------LFMIADFCQNMLAKRLMYSEELQATVLE 786
            ..:.:...||:.|..:..|                  |||..|.|
  Fly   159 GQVPICAVSALQGTHIAELREVLREAYFQPQRNLADPLFMYVDHC-------------------- 203

  Fly   787 VKALPGLGTTIDAILINGKLREGQTMVVAGTDGPIVTQIRSLL-MPQPMKELRVKNAYVEYKEVK 850
             ..:.|.||.....|:.||:                 |:.::: :|          |..|.::||
  Fly   204 -FGIKGQGTVCTGTLLQGKV-----------------QVNNVIELP----------ALGEQRKVK 240

  Fly   851 AAQGVKIAAKDLEKAIAGINLLIAHKPDEVEICTEEVARELKSALSHIKLAQTGVHVQASTLGSL 915
            :   :::..|::..|..|         |.:.:|..:.         :.||.:.|:..|...|..:
  Fly   241 S---IQMFRKNVTSASMG---------DRIGLCVTQF---------NAKLLERGIITQPGYLKPI 284

  Fly   916 EALLEFLRTSKIPYSAIRIGPVVKRDVMKASTMLEHEAQYATILAF--------DVKIEREAQEM 972
            .|:.       :.:..||....|.:.:.|....:.|....|.:..|        ..::::|.:.|
  Fly   285 YAVC-------LQFKPIRYYKEVIKSMRKMHISVGHNTVMANVTLFRDTDGTTSTFQLDKEYEYM 342

  Fly   973 ADSLGVKIFQADIIYHL--------------------------------FDKFTAYREELKQKKR 1005
            .|....::...|:||.|                                |....|::....:..:
  Fly   343 EDVQPAEVQHNDVIYALLQFESPVLSPPHSTLIASKLDMDVHSTSCRLAFWGRIAWQTHSSKYFQ 407

  Fly  1006 EEFRSVAVFPCKLRI-LPQFVFNSRDPIVMGV 1036
            ||...:.:|..|.:: ..|.|.||.:.||..:
  Fly   408 EELPKLRIFKRKQKVGSIQRVVNSSEVIVQNL 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF5B	NP_001246599.1	PRK04004	553..1129	CDD:235195	112/552 (20%)
		IF2_eIF5B	557..769	CDD:206674	63/241 (26%)
		aeIF5B_II	779..889	CDD:293904	17/110 (15%)
		IF-2	890..993	CDD:288813	21/142 (15%)
		IF2_aeIF5B_IV	1016..1110	CDD:293911	7/22 (32%)
eEFSec	NP_611584.1	SelB_euk	5..192	CDD:206676	58/227 (26%)
		SelB	6..467	CDD:225815	112/552 (20%)
		SelB_II	196..278	CDD:293897	25/150 (17%)
		eSelB_III	283..396	CDD:294009	16/119 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464657
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930