Protein Alignment eIF5B and mEFTu2

DIOPT Version :9

• Sequence 1: NP_001246599.1
• Gene: eIF5B / 44261
• FlyBaseID: FBgn0026259
• Length: 1144
• Species: Drosophila melanogaster
• Sequence 2: NP_610288.1
• Gene: mEFTu2 / 35681
• FlyBaseID: FBgn0033184
• Length: 456
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 101/486 - (20%)
• Similarity: 167/486 - (34%)
• Gaps: 136/486 - (27%)

  Fly   517 REVSVLANDPESRRLR-AEARILKRQAEAEKKRSTDELRAGVVCVLGHVDTGKTKILDKLRRTHV 580
            |.:|.....|.:.:.| ...|:|...|:........||....|..:||||.|||.:...:.|...
  Fly    18 RRISQALIGPGASQSRWTGTRLLATSADKNPAPGLRELPHCNVGTIGHVDHGKTTLTAAITRIQS 82

  Fly   581 Q----------------DSEAGGITQQIGATNVPIEAIKEQTKYVKAAAGFEHRLPGLLIIDTPG 629
            |                :.:|.|||  |.|.::         .|......:.|       .|.||
  Fly    83 QKGLAEYLSYDQIDRAPEEKARGIT--INACHI---------GYSTTERTYAH-------TDCPG 129

  Fly   630 HESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESIQLLKKKKCP-FIVALNKIDRLYDWKQLAR 693
            |..:......|:|..|.|||||....|..|||.|.:.|.|:.... .||.:||.|
  Fly   130 HADYIKNMISGASQMDGAILVVAATDGQMPQTREHLLLAKQVGIQRIIVFINKAD---------- 184

  Fly   694 RDVRDVLKEQQSNTQLEFQQRTKDVILQFAEQGLNAALFYENTDPKTYISLVPTSAISGEGMGNL 758
                  |.:|:....:|.:.|  :::..|...|:|:.:                  |.|..:..|
  Fly   185 ------LVDQEVLELVEIEMR--EMLSDFGFDGVNSPV------------------ICGSALLAL 223

  Fly   759 LFMIADFCQNMLAKRLMYSEELQAT---------VLEVK---ALPGLGTTIDAILINGKLREGQT 811
            ....::|....:.|.|...:....|         :|.:.   .:||.||.:...:..|.:.....
  Fly   224 REDKSEFGVPSIEKLLEQCDSYIPTPQRDISSPFILPIDNAFTVPGRGTVVVGTIKRGTIPRNAD 288

  Fly   812 MVVAGTDGPIVTQIRSLLMPQPMKELRVKNAYVEYKEVKAAQGVKIAAKDLEKAIAGIN---LLI 873
            ..:.|.:..:.|.|                           ..::|..|.:.:|.||.|   ||.
  Fly   289 ADLLGFNQNLKTSI---------------------------SDIQIFRKSVPQAQAGENVGALLR 326

  Fly   874 AHKPDEVE----IC---TEEVARELKSALSHIKLAQTGVHVQASTLGSLEALLEFLRTSKIPYSA 931
            ..|...||    :|   :|:::...:.::..:..|:.| .|:......::.|  |.:|..:|
  Fly   327 GIKISAVERGMLLCATGSEDISNHFEGSMYLLSRAEGG-RVKPMLSKYIQQL--FSQTWNVP--- 385

  Fly   932 IRIGPVVKRDVMKASTML---EHEAQYATIL 959
                  .:.|::.:..||   ||.....|:|
  Fly   386 ------ARIDIVPSEAMLMPGEHGQVRVTLL 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF5B	NP_001246599.1	PRK04004	553..1129	CDD:235195	93/449 (21%)
		IF2_eIF5B	557..769	CDD:206674	53/228 (23%)
		aeIF5B_II	779..889	CDD:293904	23/131 (18%)
		IF-2	890..993	CDD:288813	14/73 (19%)
		IF2_aeIF5B_IV	1016..1110	CDD:293911
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	94/451 (21%)
		EF_Tu	56..249	CDD:206671	55/246 (22%)
		EFTU_II	257..343	CDD:293898	21/112 (19%)
		mtEFTU_III	347..437	CDD:294005	14/76 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930