DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ps and HEK2

DIOPT Version :9

Sequence 1:	NP_001262415.1	Gene:	ps / 44258	FlyBaseID:	FBgn0261552	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_009521.1	Gene:	HEK2 / 852248	SGDID:	S000000128	Length:	381	Species:	Saccharomyces cerevisiae

Alignment Length:	347	Identity:	76/347 - (21%)
Similarity:	121/347 - (34%)	Gaps:	114/347 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 AQTPTATASGNTAAALASAAAAA-------------------------AAATSGGNGSSITNCNS 221
            |.||.|..:.||....:.|.:||                         ||...|..||:|:...:
Yeast     7 AATPVAIPTNNTNGGSSDAGSAATGGAPVVGTTAQPTINHRLLLSLKEAAKIIGTKGSTISRIRA 71

  Fly   222 NNSSSSSNAQQQLQLG-NYKTNSC-----WCYGESV----CSGIEVEIENNNN------------ 264
            .|:         :::| :.|...|     .|.|..:    ..|..|::.|..|
Yeast    72 ANA---------VKIGISEKVPGCSDRILSCAGNVINVANAIGDIVDVLNKRNPENEDAAEGEAE 127

  Fly   265 --------NHI------------HHGETTYHMKILVPAVASGAIIGKGGETIASLQKDTGARVKM 309
                    |||            ...|...:::::|......:||||.|.||.||....|.::..
Yeast   128 EHYYFHFLNHILPAPSKDEIRDLQQLEDIGYVRLIVANSHISSIIGKAGATIKSLINKHGVKIVA 192

  Fly   310 SKSHDFYPGTTERVCLITG----STEAIMVVMEFIMDKIREK--------PDLTNKIVDTDSKQT 362
            ||  ||.|.:.||:..|.|    .|..::.:.|.|:..:..:        |.|.....:..|..|
Yeast   193 SK--DFLPASDERIIEIQGFPGSITNVLIEISEIILSDVDVRFSTERSYFPHLKKSSGEPTSPST 255

  Fly   363 QERDKQVKILVPNSTAGMIIGKGGAFIKQIK------------------EESGSYVQISQKPTDV 409
            .. :.::::.:|....|.|||:|...||.:|                  |....::..|:.|.:|
Yeast   256 SS-NTRIELKIPELYVGAIIGRGMNRIKNLKTFTKTNIVVERKDDDDKDENFRKFIITSKFPKNV 319

  Fly   410 SLQERCI-----TIIGDKENNK 426
            .|.|..:     |.|..:||.|
Yeast   320 KLAESMLLKNLNTEIEKRENYK 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ps	NP_001262415.1	PCBP_like_KH	275..340	CDD:239089	22/68 (32%)
		PCBP_like_KH	368..433	CDD:239089	20/82 (24%)
		KH-I	696..759	CDD:238053
HEK2	NP_009521.1	KH-I_Rnc1_rpt1	44..113	CDD:411883	14/77 (18%)
		KH-I_Rnc1_rpt2	158..226	CDD:411884	22/69 (32%)
		KH	257..330	CDD:197652	15/73 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103746
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810