DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ps and fubp3

DIOPT Version :9

Sequence 1:	NP_001262415.1	Gene:	ps / 44258	FlyBaseID:	FBgn0261552	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_001007777.1	Gene:	fubp3 / 493616	ZFINID:	ZDB-GENE-041121-12	Length:	572	Species:	Danio rerio

Alignment Length:	496	Identity:	109/496 - (21%)
Similarity:	180/496 - (36%)	Gaps:	97/496 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 GGNGSSIT------NCNSNNSSSSSNAQQQLQLGNYKTNSCWCYG--ESV------CSGIEVEIE 260
            |..|..||      ||....::.|         |......|...|  ||:      ...|.....
Zfish   100 GRGGEQITRIQLESNCKIQIAADS---------GGMMDRPCTLTGTPESIEQAKRLLGQIVDRCR 155

  Fly   261 NNNNNHIHHGETTYHMKILVPAVASGAIIGKGGETIASLQKDTGARVKMSKSHDFYPGTTERVCL 325
            |....|.....::...:||:||...|.:|||||:||..||:.||.::.|.:. |..|..:::...
Zfish   156 NGPGFHSQMDGSSAVQEILIPASKVGLVIGKGGDTIKQLQERTGVKMIMIQD-DPMPTGSDKPLR 219

  Fly   326 ITGSTEAIMVVMEFIMDKIREKP--DLTNKIVDTDSKQTQERDKQVKILVPNSTAGMIIGKGGAF 388
            |:|....:....|.:::.||||.  |..:...|..|:    ....:.:.||....|::||:.|..
Zfish   220 ISGDPYKVQQARELVVEIIREKDQGDFRSGRSDFGSR----LGSSIDVAVPRFAVGIVIGRNGEM 280

  Fly   389 IKQIKEESGSYVQISQKPTDVSLQERCITIIGDKENNKNACKMILSKIVEDPQSGTCLNVSYADV 453
            ||:|:.::|  |:|..||.|....:|...::|..|..::|..:| :::|:..|.    ...:...
Zfish   281 IKKIQNDAG--VRIQFKPDDGISPDRVAQVMGQPERCQHAVHLI-NELVQTAQE----RDGFGGP 338

  Fly   454 SGPVANFNPTGSPYATNQNAINSSTASLNS-TLGTTIGGANSAASLLVNGTGINLSINLG-SPNP 516
            .||.......|.........:...|.::.: ..|..||........:...:|.::.:... .||.
Zfish   339 LGPRGRGRGRGDWNIGTPGGLQEVTYTIPADKCGLVIGKGGETIKNINQQSGAHVELQRNPPPNT 403

  Fly   517 APNLAVATQLLEHIKVAMRGSGYSETVTNEVVAALSVLAKYGVLGMG----VGVS---------H 568
            .||:..         .::|||.....:..:::.     .|.|..|||    .|:|         |
Zfish   404 DPNVRT---------FSIRGSPQQMEMARQLID-----DKIGASGMGGNSSFGLSPFTQGPATPH 454

  Fly   569 TNGAHSTLGNFLGVTTLDQQTAAAASAATASN----------------VFGAVGQVN-------- 609
            .||..:.:....|.|   .||....|....|:                .:..:||.|
Zfish   455 QNGPQTFMTGGWGTT---YQTWQPQSQQDPSHNGSQSGQMDYSKAWEQYYKKLGQQNQGQSSGPD 516

  Fly   610 ----LEQYAAAVASAAAASRPTQSQLDAAAVQFDPFRHLGS 646
                .|:|......||.......|..|.:|...:.:|..|:
Zfish   517 YSKAWEEYYKKQTQAAGPGSQQSSPPDYSAAWVEYYRQQGA 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ps	NP_001262415.1	PCBP_like_KH	275..340	CDD:239089	22/64 (34%)
		PCBP_like_KH	368..433	CDD:239089	19/64 (30%)
		KH-I	696..759	CDD:238053
fubp3	NP_001007777.1	KH-I	85..147	CDD:238053	12/55 (22%)
		KH-I	170..234	CDD:238053	22/64 (34%)
		KH-I	260..322	CDD:238053	19/63 (30%)
		KH-I	361..426	CDD:238053	12/73 (16%)
		DUF1897	535..>557	CDD:286140	4/21 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840