| Sequence 1: | NP_001262415.1 | Gene: | ps / 44258 | FlyBaseID: | FBgn0261552 | Length: | 780 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006537.3 | Gene: | IGF2BP1 / 10642 | HGNCID: | 28866 | Length: | 577 | Species: | Homo sapiens |
| Alignment Length: | 662 | Identity: | 121/662 - (18%) |
|---|---|---|---|
| Similarity: | 202/662 - (30%) | Gaps: | 296/662 - (44%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 115 ISHISNISNISNIGNISNSNHSNAAYSLAVHSYQ-------KQIESPA-NPSHVPHHQMDLSPLS 171
Fly 172 ENGSPNGTPGAQTPTATASGNTAAALASAAAAAAAATSGGNGSSITNCNSNNSSSSSNAQQQLQL 236
Fly 237 GNYKTNSCWCYGESVCSGIEVEIENNNNNHIHHGETTYHMKILVPAVASGAIIGKGGETIASLQK 301
Fly 302 DTGARVKMSKSHDFYPGTTERVCLITGSTEAIMVVMEFIMDKIREKPDLTNKIVDTDSKQTQERD 366
Fly 367 K-QVKILVPNSTAGMIIGKGGAFIKQIKEESGSYVQISQKPTDVSL--QERCITIIGDKENNKNA 428
Fly 429 CKMILSKIVEDPQSGTCLNVSYADVSGPVANFNPTGSPYATNQNAINSSTASLNSTLGTTIGGAN 493
Fly 494 SAASLLVNGTGINLSINLGSPNPAPNLAVATQLLEHIKVAMRGSGYSETVTNEVVAALSVLAKYG 558
Fly 559 VLGMGVGVSHTNGAHSTLGNFLGVTTLDQQTAAAASAATASNVFGAVGQVNLEQYAAAVASAAAA 623
Fly 624 SRPTQSQLDAAAVQFDPFRHLGSATAPAATPVSLNNNSFGLTATTGTATTAQLGGLSKSPTPGDL 688
Fly 689 SSKDSKNVEVPEVIIGAILGPSGRSLVEIQHVSGANVQISKKGIFAPGTRNRIVTITGQPSAIAK 753
Fly 754 AQYLIEQKINEE 765 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ps | NP_001262415.1 | PCBP_like_KH | 275..340 | CDD:239089 | 17/64 (27%) |
| PCBP_like_KH | 368..433 | CDD:239089 | 22/66 (33%) | ||
| KH-I | 696..759 | CDD:238053 | 20/62 (32%) | ||
| IGF2BP1 | NP_006537.3 | RRM1_IGF2BP1 | 1..77 | CDD:241069 | |
| RRM2_IGF2BP1 | 81..156 | CDD:410037 | 10/54 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 160..190 | 11/63 (17%) | |||
| Necessary for interaction with ELAVL4 and binding to TAU mRNA. /evidence=ECO:0000250 | 187..570 | 100/564 (18%) | |||
| KH-I_IGF2BP1_rpt1 | 197..272 | CDD:411918 | 20/87 (23%) | ||
| KH-I_IGF2BP1_rpt2 | 273..369 | CDD:411921 | 34/131 (26%) | ||
| Sufficient for nuclear export | 310..324 | 4/14 (29%) | |||
| KH-I_IGF2BP1_rpt3 | 404..479 | CDD:411924 | 24/76 (32%) | ||
| Sufficient for nuclear export | 485..495 | ||||
| KH-I_IGF2BP1_rpt4 | 487..562 | CDD:411927 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141633 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.840 | |||||