DRSC/TRiP Functional Genomics Resources

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Protein Alignment ps and IGF2BP1

DIOPT Version :10

Sequence 1:NP_001262415.1 Gene:ps / 44258 FlyBaseID:FBgn0261552 Length:780 Species:Drosophila melanogaster
Sequence 2:NP_006537.3 Gene:IGF2BP1 / 10642 HGNCID:28866 Length:577 Species:Homo sapiens


Alignment Length:59 Identity:15/59 - (25%)
Similarity:27/59 - (45%) Gaps:10/59 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 NIVNFFDKAHISKLGNP---KWWVRFDRPHGNVNFNHININKAITGVTDPHIKINPITA 102
            :|.::|:.|..:||...   |...|:|.      ..|::.:.|..||.| .:::.|..|
Human    29 SITSYFNSAPPAKLACSTCHKMVPRYDL------IRHLDESCANNGVGD-DVQVEPAQA 80

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
psNP_001262415.1 KH-I_NOVA_rpt1 274..345 CDD:411863
KH-I_NOVA_rpt2 367..436 CDD:411864
KH-I_NOVA_rpt3 694..762 CDD:411807
IGF2BP1NP_006537.3 RRM1_IGF2BP1 1..77 CDD:241069 13/54 (24%)
RRM2_IGF2BP1 81..156 CDD:410037 15/59 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 160..190
KH-I_IGF2BP1_rpt1 197..272 CDD:411918
KH-I_IGF2BP1_rpt2 273..369 CDD:411921
Sufficient for nuclear export 310..324
KH-I_IGF2BP1_rpt3 404..479 CDD:411924
Sufficient for nuclear export 485..495
KH-I_IGF2BP1_rpt4 487..562 CDD:411927
Blue background indicates that the domain is not in the aligned region.

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