DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab2 and Nacc1

DIOPT Version :9

Sequence 1:	NP_523879.2	Gene:	bab2 / 44254	FlyBaseID:	FBgn0025525	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_080064.3	Gene:	Nacc1 / 66830	MGIID:	1914080	Length:	514	Species:	Mus musculus

Alignment Length:	501	Identity:	100/501 - (19%)
Similarity:	169/501 - (33%)	Gaps:	160/501 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 NYQSNLTNVFDELLQSESFVDVTLSCEGHSIKAHKMVLSACSPYFQALFYDNPCQHPII-IMRDV 267
            |:.:::....:|......:.||::..:||:.|||:.||:|.|.||:.||  |..:..:: :...|
Mouse    11 NFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLF--NSSRSAVVELPAAV 73

  Fly   268 SWSDLKALVEFMYKGEINVCQDQINPLLKVAETLKIRGLAEVSAGRGEGGASALPMSAFDDEDEE 332
            .....:.::.|.|.|.:::.......|:..|..|:|:.:.|      :|....|.:|:
Mouse    74 QPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIME------KGTEFFLKVSS------- 125

  Fly   333 EELASATAILQQDGDADPDEEMKAKRPRLLPEGVLDLNQRQRKRSRDGSYATPSPSLQGGESEIS 397
                             |..:.:...|...|                 |....||..|
Mouse   126 -----------------PSCDSQGLHPEEAP-----------------SSEPQSPVAQ------- 149

  Fly   398 ERGSSGTPGQSQSQPLAMTTSTIVRNPFASPNPQTLEGRNSAMNAVANQRKSPAPTATGHSNGNS 462
               :.|.|..|...||.....|          .|.|:  :.....:|.:....:....|.|.||:
Mouse   150 ---TLGWPACSTPLPLVSRVKT----------EQELD--SVQCTPMAKRLWDSSQKEAGGSGGNN 199

  Fly   463 GAAMHSPPGGVAVQSALPPHMAAIVPPPPSAMHHHAQQLAAQHQLAHSHAMASALAAAAAGAGAA 527
            |:                 ...|....|..|::...|.|          :||:|.||.|..|
Mouse   200 GS-----------------RKMAKFSTPDLALNRMPQPL----------SMATATAAVAVVA--- 234

  Fly   528 GAGGAGSG-SGSGASAPTGGTGVAGSGAGAAVGSHHDDMEIKPEIAEMIREEERAKMIESGGHGG 591
             .||..|| |.|..::|    |.:.:....:..|:|::.:          |||     ::|..|
Mouse   235 -VGGCVSGPSMSERTSP----GTSSAYTSDSPSSYHNEED----------EEE-----DAGEEG- 278

  Fly   592 WMGAAAAATGAASVAADSYQYQLQSMWQKCWNTNQQNLVQQLRFRERGPLKSWRPEAMAEAIFSV 656
                            ...||:     |.|   |...:...|...:...    :.||:.|.:  |
Mouse   279 ----------------TDEQYR-----QIC---NMYTMYSMLNVGQTAE----KVEALPEQV--V 313

  Fly   657 LKEGLSLSQAARKFDI-PYPTFVLYANRVHNMLGPSLDGGADPRPK 701
            |:   |.|:...:.|: ..|..::  |::.|...|.|....||..|
Mouse   314 LE---SRSRIRVRQDLASLPAELI--NQIGNRCHPKLYDEGDPSEK 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab2	NP_523879.2	BTB	213..309	CDD:279045	25/96 (26%)
		BTB	224..309	CDD:197585	24/85 (28%)
		HTH_psq	645..690	CDD:283007	11/45 (24%)
Nacc1	NP_080064.3	BTB_POZ_BTBD14B_NAC1	3..125	CDD:349599	29/121 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	183..205		5/38 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	242..279		11/72 (15%)
		BEN	382..460	CDD:214981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	73	1.000	Inparanoid score	I5272
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050