DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab2 and mod(mdg4)

DIOPT Version :9

Sequence 1:	NP_523879.2	Gene:	bab2 / 44254	FlyBaseID:	FBgn0025525	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_788698.1	Gene:	mod(mdg4) / 49228	FlyBaseID:	FBgn0002781	Length:	610	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	108/483 - (22%)
Similarity:	176/483 - (36%)	Gaps:	147/483 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 EGQQFCLRWNNYQSNLTNVFDELLQSESFVDVTLSCEGHSIKAHKMVLSACSPYFQALFYDNPCQ 258
            :.:||.|.|||:.:||:..|.|.|.....|||:|:.||..:|||::|||.|||:|:.:|...|..
  Fly     3 DDEQFSLCWNNFNTNLSAGFHESLCRGDLVDVSLAAEGQIVKAHRLVLSVCSPFFRKMFTQMPSN 67

  Fly   259 -HPIIIMRDVSWSDLKALVEFMYKGEINVCQDQINPLLKVAETLKIRGLAEVSAGRGEGGASALP 322
             |.|:.:.:||.|.||.|::|||.||:||.||.:...:..||:|:|:||.
  Fly    68 THAIVFLNNVSHSALKDLIQFMYCGEVNVKQDALPAFISTAESLQIKGLT--------------- 117

  Fly   323 MSAFDDEDEEEELASATAILQQDGDADPDEEMKAKRPRLLPEGVLDLNQRQRKRSRDGSYATPSP 387
                                  |.|..|....::..|...|.    :.|:|          .|:.
  Fly   118 ----------------------DNDPAPQPPQESSPPPAAPH----VQQQQ----------IPAQ 146

  Fly   388 SLQGGESEISER-------GSSGTPGQSQSQPLAMTT----STIVRNPFASPNPQTLE------G 435
            .:|..:...|.|       ...|...||.:|.:..||    :|||:........|.::      |
  Fly   147 RVQRQQPRASARYKIETVDDGLGDEKQSTTQIVIQTTAAPQATIVQQQQPQQAAQQIQSQQLQTG 211

  Fly   436 RNSAMNAVANQRKS-------PAPTATG--HSNGNSGAAMHSP-----PGGVAVQSALPPH---- 482
            ..:....|:..::|       ||.::.|  .|..::.|.:..|     ..|....:.|.|.
  Fly   212 TTTTATLVSTNKRSAQRSSLTPASSSAGVKRSKTSTSANVMDPLDSTTETGATTTAQLVPQQITV 276

  Fly   483 MAAIVPPPPSAMHHHAQQLAAQHQ-----------------LAHSHAMASALAAAAAGAGAAGAG 530
            ..::|....:.:|..:.|...|.:                 .:..|           |..|..|.
  Fly   277 QTSVVSAAEAKLHQQSPQQVRQEEAEYIDLPMELPTKSEPDYSEDH-----------GDAAGDAE 330

  Fly   531 GA-------------------GSGSGSGASAPTGGTGVAGSGAGAAVGSHHDDMEIKPEIAEMIR 576
            |.                   ...:|:..:|.|.|.||..:.:.|.|             .:..:
  Fly   331 GTYVEDDTYGDMRYDDSYFTENEDAGNQTAANTSGGGVTATTSKAVV-------------KQQSQ 382

  Fly   577 EEERAKMIESGGHGGWMGAAAAATGAAS 604
            ....:..:::.|..|...|.||.:.:|:
  Fly   383 NYSESSFVDTSGDQGNTEAQAATSASAT 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab2	NP_523879.2	BTB	213..309	CDD:279045	44/96 (46%)
		BTB	224..309	CDD:197585	40/85 (47%)
		HTH_psq	645..690	CDD:283007
mod(mdg4)	NP_788698.1	BTB	22..118	CDD:279045	44/132 (33%)
		BTB	33..118	CDD:197585	40/121 (33%)
		FLYWCH	452..512	CDD:282369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.010