Protein Alignment bab2 and lola

DIOPT Version :10

• Sequence 1: NP_523879.2
• Gene: bab2 / 44254
• FlyBaseID: FBgn0025525
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: NP_788308.3
• Gene: lola / 44548
• FlyBaseID: FBgn0283521
• Length: 970
• Species: Drosophila melanogaster
• Alignment Length: 885
• Identity: 207/885 - (23%)
• Similarity: 327/885 - (36%)
• Gaps: 291/885 - (32%)

  Fly   194 EGQQFCLRWNNYQSNLTNVFDELLQSESFVDVTLSCEGHSIKAHKMVLSACSPYFQALFYDNPCQ 258
            :.|||||||||:||.|.:|||.||::|:.||.||:.||..:||||:|||||||||..|..:...:
  Fly     3 DDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDK 67

  Fly   259 HPIIIMRDVSWSDLKALVEFMYKGEINVCQDQINPLLKVAETLKIRGLAEVSAGRGEGGASALPM 323
            |||.|::||.:.:|:|::::||:||:|:.|||:..|||.||:|:|:||::...|   ||.:..|.
  Fly    68 HPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTG---GGVAPKPE 129

  Fly   324 SAFDDEDEEEELASATAILQQDGDADPDEEMKAKRPRLLPEGVLDL--------------NQRQR 374
            |:  ......:|:.|..:.|            .||.||...|.:|.              ::|:|
  Fly   130 SS--GHHRGGKLSGAYTLEQ------------TKRARLATGGAMDTSGDVSGSREGSSSPSRRRR 180

  Fly   375 KRSR--------DGSYATPSPSLQGGESEISERGSSGTPGQSQSQPLAMTTSTIVRNPFASPNPQ 431
            |..|        |.|.::...:....:|.:.:.|:    |.:.|   |:.|:.:...|.|..:.|
  Fly   181 KVRRRSMENDAHDNSNSSVLQAAASNQSILQQTGA----GLAVS---ALVTTQLSSGPAAGTSSQ 238

  Fly   432 TLEGRNSAMNAVANQRKSPAPTATGHSNGNSGAAMHS----PPGGVAVQSALPPHMAAIVPPPPS 492
                      |.:.|::.|. |:|..:.....|.:.|    |..|.:..:|:            .
  Fly   239 ----------ASSTQQQQPL-TSTNVTKKTESAKLTSSTAAPASGASASAAV------------Q 280

  Fly   493 AMHHHAQQLAAQHQLAHSHAMASALAAAAAGAGAAGAGGAGS--GSGSGASAPTGGTGVAGSGAG 555
            ..|.|.||  ||   ..|.|:.:....|.:..||.|..|...  ..||....|...||...:.|.
  Fly   281 QAHLHQQQ--AQ---TTSDAINTENVQAQSQGGAQGVQGDDEDIDEGSAVGGPNSATGPNPASAS 340

  Fly   556 AAV-----------------GSHH-------------DDMEIKPE-----------IAEMIREEE 579
            |:.                 .|:|             .:|.|:|:           :.::..:||
  Fly   341 ASAVHAGVVVKQLASVVDKSSSNHKHKIKDNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEE 405

  Fly   580 RAKMIESGGHGGW-MGAAAAATGAASVAADSYQYQLQSMWQKCWNTNQQNLVQQLRFRERGPLKS 643
            ...|.|.....|. .|...::...|:...|..|.:|..|.|.....:.|...|....:..|....
  Fly   406 DMTMEELDQTAGTSQGGEGSSQTYATWQHDRSQDELGLMAQDAQQRDPQASKQDKGEQTEGAQDE 470

  Fly   644 WR-PEAMAEA---IFSVLKEGLSLSQAARKFDIPYPTFVLYANRVHNMLGPSLD----------- 693
            :. .:.:.|:   :.:..|:|                |||:..::.|:....|:
  Fly   471 FELDDCLLESNDIVITQNKDG----------------FVLHVKKLGNITAAKLEENQAVAQQQGQ 519

  Fly   694 ------GGA-DPRP------------KARGRPQRILLGMWPEELIRSVIKAVVFRDYREIKEDMS 739
                  |.| .|.|            .:..:|....|...|.:|..|..:.:      .||:.:.
  Fly   520 AAVTVTGPAGQPTPTITELLNAAAASHSEPKPTLTTLTSTPIKLPSSECELI------NIKKIIP 578

  Fly   740 AHQYANGQGHGTYIGGGTTTNGYHSAAAAKLAAQNAALAPPDAGSPLSSMTETLRRQILSQQQQH 804
            |                |||...|.               |...|.:......:  |.:||:..|
  Fly   579 A----------------TTTIATHH---------------PHTSSTIIHPHHII--QHVSQEPHH 610

  Fly   805 QQHHQQ-------------QAHHQQ---------QPSHHQQQS---------------------- 825
            |:||||             |.||||         ||:|.|.||
  Fly   611 QEHHQQHQTIHIEEVPQTSQQHHQQQHHHQLQTVQPTHTQVQSIITAHPGQTINLVGLRNVQLAD 675

  Fly   826 -----------------PHAQSMNMYKS--PAYLQRSEIED----QVS--------AAAAVAAAA 859
                             |..|::.:.::  |...|..|:.|    ::|        |:||:.:..
  Fly   676 SKPIASRIRYSRGKIIGPTVQNLQIVETHEPIQHQHHELSDGTKYEISEIDLNNPNASAAIISDL 740

  Fly   860 AKHQQQQGERRGSENLPDLSALGLMGLPGLNVMPSRGSGG 899
            .|:.:..     ...|||.:.:|:...|.......:.|||
  Fly   741 VKYAEID-----DIELPDGTKIGIGFAPSEITEHMQTSGG 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bab2	NP_523879.2	BTB_POZ_BAB-like	222..305	CDD:349624	43/82 (52%)
		HTH_psq	645..690	CDD:283007	7/48 (15%)
lola	NP_788308.3	BTB_POZ_BAB-like	31..114	CDD:349624	43/82 (52%)
		C2H2 Zn finger	905..925	CDD:275368
		zf-H2C2_5	935..957	CDD:404746
		C2H2 Zn finger	935..955	CDD:275368