DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bab2 and CG6765

DIOPT Version :9

Sequence 1:	NP_523879.2	Gene:	bab2 / 44254	FlyBaseID:	FBgn0025525	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	773	Identity:	152/773 - (19%)
Similarity:	242/773 - (31%)	Gaps:	243/773 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 QQFCLRWNNYQSNLTNVFDELLQSESFVDVTLSCEGHS-----------IKAHKMVLSACSPYFQ 249
            :.:.|:|:::.:.|.:....|.::|.|.||.|....:|           |.|||.:|||.|.:|.
  Fly     4 ENYHLKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILSASSQFFA 68

  Fly   250 ALFYDNPCQHP-----IIIMRDVSWSDLKALVEFMYKGEINVCQDQINPLLKVAETLKIRGLAEV 309
            .:|...|..:|     :::..|:|...::.||::||.||..|..|.:|.:|:..|.||||||...
  Fly    69 TMFETAPITNPNGVLYVVLPPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILKIRGLCRT 133

  Fly   310 SAGRGEGGASALPMSAFDDEDEEEELASATAILQQDGDADPDEEMKAKRPRLLPEGVLDLNQRQR 374
            |:..|.|..|.:..:     .....||         |...|.|
  Fly   134 SSSNGGGSGSVVTTT-----HHPHSLA---------GHLHPRE---------------------- 162

  Fly   375 KRSRDGSYATPSPSLQGGESEISERGSSGTPGQSQSQPLAMTTSTIVRNPFASPNPQTLEGRNSA 439
                                               :..:.|:..|....|...|.||:.......
  Fly   163 -----------------------------------ASTMYMSNGTRTALPPPPPPPQSTMSAQLQ 192

  Fly   440 MNAVANQRKSPAPTATGH---SNGNSGAAMHSPP---GGVAVQSALPPHMAAIVPPPPSAMHHHA 498
            .:..|::.......|..|   |:.:|....|:|.   .|:.. |.:|.....|:..|..|.|...
  Fly   193 GDLYASKPGGSTRFALDHHHLSSHHSHLNHHNPQQQFRGLGA-SVMPKDSPVIIKSPKLAAHTGL 256

  Fly   499 QQLAAQHQL-------------------------AHSHAMASALAAAAAGAGAAGAGGAGSGSGS 538
            ..:|:..:|                         :.||...........|    |.||:..|||:
  Fly   257 LTVASSSKLGISVNKEVAIDPEDKCCFAAPGQLESQSHPPPPTTTTTTVG----GGGGSVGGSGA 317

  Fly   539 GASAPTG-GTGVAGSGAGAAVGSHHDDMEIKPEIAEMIREEERAKMIESGGHGGWMGAAAAATGA 602
            ..|.|.. .|.|..|......|...|..|      ..:|..|
  Fly   318 PPSQPISICTEVGCSSCPLTAGPGADQAE------TTLRRTE----------------------- 353

  Fly   603 ASVAADSYQYQLQSMWQKCWNTNQQNLVQQLRFRERGPLKSWRPEAMAEAIFSVLKEGLSLSQAA 667
                     |:.|::.::    |:..||.:.|.|.....:..|....|.....|:...|:.:...
  Fly   354 ---------YEEQALRER----NEVGLVFERRLRRESACERSRDYYEAPHFEHVVSSRLAATPPP 405

  Fly   668 RKFDIP--------YPTFVL--------YANRVHNMLGPSLDGGADPRPKARGRPQRILLGMWPE 716
            .....|        :|...|        ::|...|....|.:...:..|.|  .|::      |.
  Fly   406 PPQQAPPSHPPTLRHPHNFLTIKQEPTDWSNNPPNASSASNNNNLEELPLA--SPKQ------PL 462

  Fly   717 ELIRSVIKAVVFRDYREIKEDMSAH---QYANGQ-------------------GH-GTYIG---G 755
            :...|.:|..|.||.....|:...|   .|.|.:                   .| ||:.|   |
  Fly   463 DFKMSAVKLEVNRDRGTPSEESEEHTLRDYNNFKQLLVCEICQKSFEDTKMLVRHLGTHAGDPTG 527

  Fly   756 GTTTNGYHSAAAAKL--AAQNAALAPPDAGSPLSSMTETLRRQILSQQQQHQQHHQQQAHHQQQP 818
            ||..|...|:|:...  |:.|.||.......|       .:|:.:|||:.:..|...........
  Fly   528 GTERNLLPSSASGSTTSASSNLALRSVKTYVP-------KKRRRVSQQENNMDHDHVTLLCDLCS 585

  Fly   819 SHHQQQSPHAQSMNMYKSPAYLQRSEIEDQVSAAAAVAAAAAKHQQQQGERRGSENLP 876
            :.....:...:.||.       |.:|||           .|..:.::.||::|.:..|
  Fly   586 TSFDTPAEWVRHMNS-------QHTEIE-----------LAMFNSKKDGEQKGQQPPP 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab2	NP_523879.2	BTB	213..309	CDD:279045	38/111 (34%)
		BTB	224..309	CDD:197585	35/100 (35%)
		HTH_psq	645..690	CDD:283007	9/60 (15%)
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	38/107 (36%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	29/76 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447061
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940