DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab2 and Nacc1

DIOPT Version :9

Sequence 1:	NP_523879.2	Gene:	bab2 / 44254	FlyBaseID:	FBgn0025525	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	XP_006255276.1	Gene:	Nacc1 / 171454	RGDID:	621003	Length:	540	Species:	Rattus norvegicus

Alignment Length:	548	Identity:	106/548 - (19%)
Similarity:	184/548 - (33%)	Gaps:	175/548 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 LFEFGQ-RSSPVETKIKTNPETKPPRRKIVPPSGEGQQFCLRWNNYQSNLTNVFDELLQSESFVD 224
            :|..|: ||..::..:..|      ||  .|.:...|...:...|:.:::....:|......:.|
  Rat     1 MFAGGRTRSETIDVGVNYN------RR--APAAAMAQTLQMEIPNFGNSILECLNEQRLQGLYCD 57

  Fly   225 VTLSCEGHSIKAHKMVLSACSPYFQALFYDNPCQHPII-IMRDVSWSDLKALVEFMYKGEINVCQ 288
            |::..:||:.|||:.||:|.|.||:.||  |..:..:: :...|.....:.::.|.|.|.:::..
  Rat    58 VSVVVKGHAFKAHRAVLAASSSYFRDLF--NSSRSAVVELPAAVQPQSFQQILTFCYTGRLSMNM 120

  Fly   289 DQINPLLKVAETLKIRGLAEVSAGRGEGGASALPMSAFDDEDEEEELASATAILQQDGDADPDEE 353
            .....|:..|..|:|:.:.|      :|....|.:|:                        |..:
  Rat   121 GDQFLLIYTAGFLQIQEIME------KGTEFFLKVSS------------------------PSCD 155

  Fly   354 MKAKRPRLLPEGVLDLNQRQRKRSRDGSYATPSPSLQGGESEISERGSSGTPGQSQSQPLAMTTS 418
            .:...|.                      ..||...|...::|     .|.|..|...||.....
  Rat   156 SQGLHPE----------------------EAPSSEPQSPVAQI-----LGWPACSTPLPLVSRVK 193

  Fly   419 TIVRNPFASPNPQTLEGRNSAMNAVANQRKSPAPTATGHSNGNSGA---AMHSPPGGVAVQSALP 480
            |          .|.|:  :.....:|.:....:....|.|.||:|:   |..|.|.       |.
  Rat   194 T----------EQELD--SVQCTPMAKRLWDSSQKEAGGSGGNNGSRKMAKFSTPD-------LA 239

  Fly   481 PHMAAIVPPPPSAMHHHAQQLAAQHQLAHSHAMASALAAAAAGAGAAGAGGAGSG-SGSGASAPT 544
            |:.   :|.|.|                        :|.|.|.......||..|| |.|..::|
  Rat   240 PNR---MPQPVS------------------------VATATAAVAVVAVGGCVSGPSMSERTSP- 276

  Fly   545 GGTGVAGSGAGAAVGSHHDDMEIKPEIAEMIREEERAKMIESGGHGGWMGAAAAATGAASVAADS 609
               |.:.:....:..|:|::.:          |||     ::|..|                .|.
  Rat   277 ---GTSSAYTSDSPSSYHNEED----------EEE-----DAGEEG----------------TDE 307

  Fly   610 YQYQLQSMWQKCWNTNQQNLVQQLRFRERGPLKSWRPEAMAEAIFSVLKEGLSLSQAARKFDI-P 673
            ...|:.:|:......|....|:::             ||:.|.:  ||:   |.|:...:.|: .
  Rat   308 QYRQICNMYTMYSMLNVGQTVEKV-------------EALPEQV--VLE---SHSRIRVRQDLAS 354

  Fly   674 YPTFVLYANRVHNMLGPSLDGGADPRPK 701
            .|..::  |::.|...|.|....||..|
  Rat   355 LPAELI--NQIGNRCHPKLYDEGDPSEK 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab2	NP_523879.2	BTB	213..309	CDD:279045	25/96 (26%)
		BTB	224..309	CDD:197585	24/85 (28%)
		HTH_psq	645..690	CDD:283007	11/45 (24%)
Nacc1	XP_006255276.1	BTB	46..147	CDD:279045	27/108 (25%)
		BTB	57..148	CDD:197585	26/98 (27%)
		BEN	408..486	CDD:214981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I5180
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050