DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab2 and btbd18

DIOPT Version :9

Sequence 1:	NP_523879.2	Gene:	bab2 / 44254	FlyBaseID:	FBgn0025525	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	XP_017951392.1	Gene:	btbd18 / 100498010	-ID:	-	Length:	602	Species:	Xenopus tropicalis

Alignment Length:	267	Identity:	66/267 - (24%)
Similarity:	105/267 - (39%)	Gaps:	62/267 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 WNNYQSNLTNVFDELLQSES---FVDVTL-SCEGHSIKAHKMVLSACSPYFQALF---------- 252
            ||  ...|..:|.:|.:.::   |.|||| ..||..:..|..:|:|||||...|.
Frog    10 WN--PRLLRTMFLQLQRQQNTGFFCDVTLQGGEGEGVSVHACLLAACSPYLAKLLASVTEVSQLD 72

  Fly   253 ----YDNPCQHPIIIMRDVSWSDLKALVEFMYKGEINVCQDQINPLLKVAETLKIRGLAEVSAGR 313
                ....|...|:.:..:....|..||.:||..|:.|..:.::.:|:.|..|:|   .|:...|
Frog    73 TDSAIQTDCTGHILTVPGIPSCYLLPLVHYMYTSELEVTPENVHGVLEAARRLQI---PELEGLR 134

  Fly   314 GEGGASALPMSAFDDEDEEEELAS-------ATAILQ---QDGDAD---PDEEMKAKR---PRLL 362
            .|||....|           |||.       .:.|.|   :.|:..   ..||:.:.|   .|:.
Frog   135 LEGGRLVRP-----------ELARKLNRDCFGSVISQYATESGNGKQIFTKEEITSGRNVPVRMH 188

  Fly   363 PEGVLDLNQRQRKRSRDGSYATPSPSLQGGESEISERGSSGTPGQSQSQPLAMTTSTIVRNPFAS 427
            .:|...|.:|..|   :.::...:.||..|:.|    .||...|..::..|.:|     :||...
Frog   189 EQGPCILEKRTNK---EHTFPADTGSLLRGKME----ASSSLQGNIENPLLEIT-----KNPTEK 241

  Fly   428 PNPQTLE 434
            ..|.|::
Frog   242 SGPSTVQ 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab2	NP_523879.2	BTB	213..309	CDD:279045	30/113 (27%)
		BTB	224..309	CDD:197585	27/99 (27%)
		HTH_psq	645..690	CDD:283007
btbd18	XP_017951392.1	BTB_POZ_BTBD18	17..148	CDD:349602	39/144 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910