DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab2 and Btbd18

DIOPT Version :9

Sequence 1:	NP_523879.2	Gene:	bab2 / 44254	FlyBaseID:	FBgn0025525	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	XP_002729248.1	Gene:	Btbd18 / 100363270	RGDID:	2323370	Length:	724	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	77/323 - (23%)
Similarity:	115/323 - (35%)	Gaps:	76/323 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 QSESFVDVTLSCEGHSIKAHKMVLSACSPYF-QALFYDNPCQHPIIIMR--DVSWSDLKALVEFM 279
            ||..|.|..|..||.::.||..:||||||:| :.|..:.|.|...:::.  .:....|:.||:|:
  Rat    29 QSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLELGGLKIQTLRKLVDFL 93

  Fly   280 YKGEINVCQDQINPLLKVA--------ETLKIRG--LAEVSAGRGEGGASALPMSAFDDEDEEEE 334
            |..|:.|.|::...:|..|        |||::.|  |.:...||........|.||..
  Rat    94 YTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNRECLQPPSAAP------- 151

  Fly   335 LASATAILQQDGDADP------------------DEEMKAKRPRLLPEG-----VLDLNQRQRKR 376
             .||..::.:.....|                  .||..|.:...||..     .|.|.::.|..
  Rat   152 -ISARVVVPRSRPRTPLPVTQTPSPLGAVKLKSLGEEEGAHKKSNLPNADNLSDTLLLKKKARVC 215

  Fly   377 SRDGSYATPSPSLQGGESEISERGSSGTPG-----QSQSQPLAMTTSTIVRNPFASPNPQTLEGR 436
            ......::||...:|.:...|..||:..|.     ..|..|..:..|.      :.|:|.....:
  Rat   216 LTQERSSSPSSQREGPKENKSNPGSTALPSLYPSVDEQLLPRKIRLSR------SKPSPHVYTSK 274

  Fly   437 NSAMNAVANQRKSPAPTATGH--------SNGNSGAAMHSPPGGVAVQSALPPHMAAIVPPPP 491
            .|:|.:    ..|..|||.|.        |....|.....|.....:||         .|.||
  Rat   275 PSSMLS----GPSSMPTAPGRRLWRQRTVSEATQGVDKQKPGEVSTLQS---------TPDPP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab2	NP_523879.2	BTB	213..309	CDD:279045	34/103 (33%)
		BTB	224..309	CDD:197585	31/97 (32%)
		HTH_psq	645..690	CDD:283007
Btbd18	XP_002729248.1	BTB	24..123	CDD:279045	30/93 (32%)
Btbd18	XP_002729248.1	BTB	35..123	CDD:197585	27/87 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910