Protein Alignment Cpsf160 and pic

DIOPT Version :9

• Sequence 1: NP_995833.1
• Gene: Cpsf160 / 44250
• FlyBaseID: FBgn0024698
• Length: 1455
• Species: Drosophila melanogaster
• Sequence 2: NP_650257.1
• Gene: pic / 41611
• FlyBaseID: FBgn0260962
• Length: 1140
• Species: Drosophila melanogaster
• Alignment Length: 1519
• Identity: 268/1519 - (17%)
• Similarity: 522/1519 - (34%)
• Gaps: 481/1519 - (31%)

  Fly    12 TAVEFSIACRFFNNLDENLVVAGANVLKVYRIAPNVEASQRQKLNPSEMRLAPKMRLECLATYTL 76
            |||...:...|.:..|.||::|..|.:::..:.|       :.|.|             |....:
  Fly    13 TAVVACLTGNFTSPTDLNLIIARNNQVEIDLVTP-------EGLRP-------------LKEINI 57

  Fly    77 YGNVMSLQCVSLAGAMRDALLISFKDAKLSVLQ----HDPDTFALKTLSLHYFEEDDIRGGWTGR 137
            .|.:..::......:.:|.|.|..:...:.:|:    :|..|...|.           .|..:..
  Fly    58 NGTIAVMRHFRPPDSNKDLLFILTRRYNVMILEARMVNDVITVVTKA-----------NGNVSDS 111

  Fly   138 YFVPT-----VRVDPDSRCAVMLVYGKRLVVLPFRKDNSLDEIELADVKPIKKAPTAMVSRTPIM 197
            ..:|:     ..:||.:|...|.:|.....::|..||.|  |::..:::
  Fly   112 VGIPSEGGVIAAIDPKARVIGMCLYQGLFTIIPMDKDAS--ELKATNLR---------------- 158

  Fly   198 ASYLIALRDLDEKIDNVLDIQFLHGYYEPTLLILYEPVRTCPGRIKVRSDTCVLVAISLNIQQR- 261
                     :||.  ||.|::||||...||::::::.           ||...:.:..:|::.:
  Fly   159 ---------MDEL--NVYDVEFLHGCLNPTVIVIHKD-----------SDGRHVKSHEINLRDKE 201

  Fly   262 VHPIIWTVNSLPFDCLQVYPIQKPIGGCLVMTVNAVIYLNQS----VPPYGVSLNSSADNSTAFP 322
            ...|.|..:::..:...:.|:..||||.:|:...:::|.:.|    |.|  ::...|..|..|
  Fly   202 FMKIAWKQDNVETEATMLIPVPSPIGGVIVIGRESIVYHDGSNYHAVAP--LTFRQSTINCYA-- 262

  Fly   323 LKPQDGVRISLDCANFAFIDVDKLVISLRTGDLYVLTL-CVDSMR--TVRNFHFHKAAASVLTSC 384
                   |:|.:...:...::|        |.||:|.| ..::.:  ||::....:.....:..|
  Fly   263 -------RVSSNGLRYLLGNMD--------GQLYMLFLGTAETSKGVTVKDIKVEQLGEISIPEC 312

  Fly   385 ICVLHSEYIFLGSRLGNSLLLHFTEE--DQSTVITLDEVEQQSEQQQRNLQDEDQNLEEIFDVDQ 447
            |..|.:.::::|:|.|:|.|:....|  |.|.|:.::..               .||..|.|:..
  Fly   313 ITYLDNGFLYIGARHGDSQLVRLNSEAIDGSYVVPVENF---------------TNLAPILDIAV 362

  Fly   448 LEMAPTQAKSRRIEDEELEVYGSGAKASVLQLRKFIFEVCDSLMNVAPINYMCAGERVEFEEDGV 512
            :               :|:..|.|
  Fly   363 V---------------DLDRQGQG----------------------------------------- 371

  Fly   513 TLRPHAESLQDLKIELVAATGHSKNGALSVFVNCINPQIITSFELDGCLDVWTV---FDDATKKS 574
                          :::..:|..|:|:|.:....|..|.....:|.|...:|::   .|::..::
  Fly   372 --------------QIITCSGSFKDGSLRIIRIGIGIQEHACIDLPGIKGMWSLKVGVDESPYEN 422

  Fly   575 SRNDQHDFMLLSQRNSTLVLQ-TGQEINEIENTGFTVNQPTIFVGNLGQQRFIVQVTTRHVRLLQ 638
            :       ::|:....|.:|. :|:|:.|.|..||..:..|....|:...: ::|||:..|||:.
  Fly   423 T-------LVLAFVGHTRILTLSGEEVEETEIPGFASDLQTFLCSNVDYDQ-LIQVTSDSVRLVS 479

  Fly   639 GTRLIQNVPIDVGSPVVQVSIADPYVCLRVLNGQVITLAL-RETRGTPRLAINKHTISSSPAVVA 702
            ..                                  |.|| .|.|.|....|...:.:::..:||
  Fly   480 SA----------------------------------TKALVAEWRPTGDRTIGVVSCNTTQILVA 510

  Fly   703 ISAYKDLSGLFTVKGDDINLTGSSNSAFGHSFGGYMKAEPNMKVEDEEDLLYGDAGSAFKMNSMA 767
            .:.     .:|.:..:|.:|...|....                             |:::..:.
  Fly   511 SAC-----DIFYIVIEDGSLREQSRRTL-----------------------------AYEVACLD 541

  Fly   768 DLAKQSKQKNSDWWRRLLVQAKPSYWLVVARQSGTLEIYSMPDMKLVYLVNDVGNGSMVLTDAME 832
            .......||.||     ||..  ..|..:     :..|.|:||::.:|.....|          |
  Fly   542 ITPLDETQKKSD-----LVAV--GLWTDI-----SAVILSLPDLETIYTEKLSG----------E 584

  Fly   833 FVP--ISLTTQENSKAGIVQACMPQHANSPLPLELSVIGLGLNGERPLLLVRTRVELLIYQVFRY 895
            .:|  |.:||.|.                 :...|..:|.|               .:.|.:...
  Fly   585 IIPRSILMTTFEG-----------------IHYLLCALGDG---------------SMYYFIMDQ 617

  Fly   896 PKGHLKIRFRKMDQLNLLDQQPTHIDLDENDEQEEIESYQMQPKYVQKLRPFANVGGLSGVMVCG 960
            ..|.|..: :|:    .|..|||                        .||.|.:: ..:.|..|.
  Fly   618 TTGQLTDK-KKV----TLGTQPT------------------------TLRTFRSL-STTNVFACS 652

  Fly   961 VNPCFVFLTFRGELRIHRLLGNGDVRSFAAFNNVNIP--------NGFLYFDT-TYELKISVLPS 1016
            ..|..::.:      .|:|:          |:|||:.        |...|.|: ....|.:|:..
  Fly   653 DRPTVIYSS------NHKLV----------FSNVNLKEVNHMCSLNAQAYPDSLALANKNAVILG 701

  Fly  1017 YLSYDSVWPVRKVPLRCTPRQLVYHRENRVYCLITQT--------EEPMTKYYRFNGEDKELSEE 1073
            .:.......:|.|||...||::.|...::.:.:.|..        .:|:.     |....:....
  Fly   702 TIDEIQKLHIRTVPLGEGPRRIAYQESSQTFAVSTLRIDVHGRGGAKPLR-----NSASTQAQNI 761

  Fly  1074 SRGERFI------------YPIGSQFE---MVLISPETWEIVPDASITFEPWEHVTAFKIVKLSY 1123
            :....|:            ..:|.:.:   :::|...|:|::  .:..|...|.:::....||..
  Fly   762 TCSSNFLPKPGGGNSTAANAEVGQEIDVHNLLVIDQNTFEVL--HAHQFVAPETISSLMSAKLGD 824

  Fly  1124 EGTRSGLKEYLCIGTNFNYSEDITSRGNIHIYDIIEVVPEPGKPMT---------KFKIKEIFKK 1179
            :.     ..|..:.|:.                   |:||..:|..         :.|:.::.:.
  Fly   825 DP-----NTYYVVATSL-------------------VIPEEPEPKVGRIIIFHYHENKLTQVAET 865

  Fly  1180 EQKGPVSAISDVLGFLVTGLGQ--KIYIW----QLR----DGDLIGVAFIDTNIYVHQIITVKSL 1234
            :..|...|:.:..|.::.|:|.  ::|.|    :||    ..::|...|:...         ...
  Fly   866 KVDGTCYALVEFNGKVLAGIGSFVRLYEWTNEKELRMECNIQNMIAALFLKAK---------GDF 921

  Fly  1235 IFIADVYKSISLLRFQEEYRTLSLASRDFNPLEVYGIEFMVDNSNLGFLVTDAERNIIVYMYQPE 1299
            |.:.|:.:||:||:.::........:||..|..:..:|.:.|::   ||.::...|:.|......
  Fly   922 ILVGDLMRSITLLQHKQMEGIFVEIARDCEPKWMRAVEILDDDT---FLGSETNGNLFVCQKDSA 983

  Fly  1300 ARESLGGQKLLRKADYHLGQVVNTMFRVQCHQKGLHQRQPFLYENKHFVVYGTLDGALGYCLPLP 1364
            |......|.|...|.:|||..||.........:.:.:|...:   ...|:|||.:||:|....:|
  Fly   984 ATTDEERQLLPELARFHLGDTVNVFRHGSLVMQNVGERTTPI---NGCVLYGTCNGAIGIVTQIP 1045

  Fly  1365 EKVYRRFLMLQNVLLSYQEHLCGLNPKEYRTLKSSKKQGINPSRCIIDGDLIWSYRLMANSERNE 1429
            :..|.....|:..|....:.:..:....||..:.:.|  :.||...||||||.|:..::..:..:
  Fly  1046 QDFYDFLHGLEERLKKIIKSVGKIEHTYYRNFQINSK--VEPSEGFIDGDLIESFLDLSRDKMRD 1108

  Fly  1430 VAKKI-----GTRTEEILGDLLEI 1448
            ..:.:     |.|....:.|:::|
  Fly  1109 AVQGLELTLNGERKSADVEDVIKI 1132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf160	NP_995833.1	SFT1	1..1453	CDD:227490	268/1519 (18%)
		MMS1_N	94..674	CDD:287414	104/602 (17%)
		CPSF_A	1086..1419	CDD:281209	72/354 (20%)
pic	NP_650257.1	SFT1	13..1139	CDD:227490	268/1519 (18%)
		MMS1_N	75..542	CDD:287414	118/697 (17%)
		CPSF_A	792..1100	CDD:281209	73/350 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472752
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10644
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940