Protein Alignment Cpsf160 and mms1

DIOPT Version :9

• Sequence 1: NP_995833.1
• Gene: Cpsf160 / 44250
• FlyBaseID: FBgn0024698
• Length: 1455
• Species: Drosophila melanogaster
• Sequence 2: NP_592998.1
• Gene: mms1 / 2543633
• PomBaseID: SPAC3H8.05c
• Length: 1073
• Species: Schizosaccharomyces pombe
• Alignment Length: 1410
• Identity: 241/1410 - (17%)
• Similarity: 431/1410 - (30%)
• Gaps: 507/1410 - (35%)

  Fly    72 ATYTLYGNVMSLQCVSLAGAMRDALLISFKDAKLSVLQHDPDTFALKTLSLHYFEEDDIRGGWTG 136
            |...|.|:..|:..|||   .|...|:.|:...|..     .|.::..||.|:.:.:      :|
pombe    23 APLLLLGSFSSVASVSL---KRSGDLLLFERFTLPA-----RTRSVALLSSHFLQSE------SG 73

  Fly   137 RYFVPTVRVDPDS-RCAVMLVYGKRLVVLPFRKDNSLDEIELADV--------------KPIKKA 186
            |:.:..:.:..:: :|     |..:||..|   :.:...|.:.|.              |.|...
pombe    74 RHSIANILIATENGKC-----YLLQLVKTP---EKAFPTIRIRDEFVLDTRMYNHEQLGKSIDLC 130

  Fly   187 PTAMVSRTPIMASYLIAL----RDLDEKIDNVLDIQ--FLHGYYEPTLLILYEPVRTCPGRIKVR 245
            |.|.:..|...|..::..    ..|.:::...|.|.  .||..:.|            |.|....
pombe   131 PNASLWATNSFAGDIVFFFSHHPSLSKQVFAQLSIDGIILHTIFVP------------PKRSSSS 183

  Fly   246 SDTCVLVAISLNIQQRVHPIIWTVNSLPFDCLQVYPIQKPIGGCLVMTVNAVIYLNQSVP-PYGV 309
            ..|.|.:.:..|...|::...|:......|                    |..|:..|:| |...
pombe   184 CVTYVCLFLDSNSNPRINVYRWSKTETFSD--------------------ASSYITFSIPVPSEF 228

  Fly   310 SLNSSADNSTAFP--------------LKPQDGVRISLDCANFAFIDVDKLVISLRTGDLYVLTL 360
            ||.|.....:..|              ..||      ::|.:..|:..|   :.......|.|::
pombe   229 SLASHIIPCSNIPDHFLVLLETKICLLSVPQ------IECGDLKFLQTD---LPCSGSHNYPLSI 284

  Fly   361 CVDS------MRTVRNFHFHKAAASVLTSCICVLHSEYIFLGSRLGNSLL-----LHFTEEDQST 414
            ..|:      ..|..|...::...|:|:..|.::..    .||.|||.:|     :.|..:...|
pombe   285 ANDNETPNCCYLTYENGDLYRIRYSILSIDINLIGK----TGSSLGNLILPCYPYIVFCGDCSDT 345

  Fly   415 VITLDEVEQQ-----------------SEQQQRNLQDEDQNLEEIFDVDQLEMAPTQAKSRRIED 462
            ::....|...                 |..:...|.|||.|...::
pombe   346 LVYDVSVSPMSFFGSLIACAPMWDFVYSSSRHNTLLDEDINCNTVY------------------- 391

  Fly   463 EELEVYGSGAKASVLQLRKFIFEVCDSLMNVAPINYMCAGERVEFEEDGVTLRPHAESLQDLKIE 527
               ...|.|....::.:|                 |.|:         ..||      |:.:..|
pombe   392 ---ATAGIGKSGCLVTMR-----------------YGCS---------STTL------LEAILTE 421

  Fly   528 LVAATGHSKNGALSVFVNCI----NPQIITSFELDGCLDVWTVFDDATKKSSRNDQHDFMLLSQR 588
            ....:|...:...|.|...:    ..||: ...|||      |.:|.|:....:|.....:::.:
pombe   422 GAVLSGIINSNHNSEFYAWLTYPWQTQIL-RLHLDG------VVEDVTESLFLDDIKALYVINYQ 479

  Fly   589 NSTLVLQTGQEI----------NEIENTG-----FTVNQPTIFVGNLGQQRFIVQVTTRHVRLL- 637
            | |.::.||:.|          |.:|.:|     .......||:.......|..|:.|..:..|
pombe   480 N-TFIIITGKSIYAVTPSCTKYNLLEVSGDEEFVLAAYNELIFIVKKDLMNFKSQLLTLKLNTLS 543

  Fly   638 QGTRLIQNVP-----IDVGSPVVQVSIADPYVCLRVLNGQVITLALRETRGTPRLAINKHTISSS 697
            .||..:|::|     .||.:.:...|:....:.:.|...........:.        ..|:
pombe   544 NGTLELQSLPDSFDLHDVPTCITSFSLERKLLVILVHPSPYFECVFYDE--------TSHS---- 596

  Fly   698 PAVVAISAYKDLSGLFTVKGDDINLTGSSNSAFGHSFGGYMKAEPNMKVEDEEDLLYGDAGSAFK 762
                  |.||            :.||       |..||                         :.
pombe   597 ------SVYK------------VPLT-------GFQFG-------------------------YL 611

  Fly   763 MNSMADLAKQSKQKNSDWWRRLLVQAKPSYWLVVARQSGTLEIY------SMPDMKLVYLVNDVG 821
            .:|::.|.|.::                :.:::::..|..|.:|      .:||.| ||
pombe   612 PHSISYLRKSNR----------------AVYVLISSNSTLLTVYVTLTLEGVPDFK-VY------ 653

  Fly   822 NGSMVLTDAMEFVPISLTTQENSKAGIVQACMPQHANSPLPLELSVIGLGLNGERPLLLVRTRVE 886
             .:.:.||    :|::|.:..:..:.|       :|.|..   |.::|:.:..|:|.|
pombe   654 -SNPISTD----LPLTLQSPSDEFSTI-------YAWSDY---LYIVGIDMETEQPTL------- 696

  Fly   887 LLIYQVFRYPKGHLKIRFRKMDQLNLLDQQPTHIDLDENDEQEEIESYQMQPKYVQKLRPFANVG 951
                                 :|:           |:.||.                   |..|.
pombe   697 ---------------------NQI-----------LEVNDS-------------------FTCVS 710

  Fly   952 GLSGVMVCGVNPCFVFLTFRGELRIHRLLGNGDVRSFAAFNNVNIPNGFLYFDTTYELKISVLPS 1016
            |:                                        .:|||.|...::...:..|....
pombe   711 GI----------------------------------------YDIPNKFQNSESRIIVYYSNNTL 735

  Fly  1017 YLSYDSVW-PVR----KVPLRCTPRQLVYHRENRV------YCLITQTEEPMTKYYRFNGEDKEL 1070
            |||  .:| |.|    |:.|..||::|:..:....      :.|:.:.......:|...  :..|
pombe   736 YLS--ELWLPQRTFSSKLNLAATPKRLLVDKYTNTLIIGCCHVLVNEITTSGLAFYDLT--NSRL 796

  Fly  1071 ------SEESRGERFIYPIGSQFEMVLISPETWEIVPDASITFEPWEHVTAFKIVKLSYEGTRSG 1129
                  |.:.:|:....|     |.:|.|...|.:..|.                |..|
pombe   797 FPVNWPSMDIKGKPIFKP-----EELLYSMSFWIVADDQ----------------KRKY------ 834

  Fly  1130 LKEYLCIGTNFNYSEDITSRGNIHIYDIIEVVPEPGKPMTKFKIKEIFKKEQKGPVSAISDV-LG 1193
              .||||||....:...|.|       ::.:...........:::.:.....|.|:.::..: ..
pombe   835 --RYLCIGTGVRKNGLTTGR-------LLILTMNKDHDSNAIELRNVITINMKDPIYSVCSIGKH 890

  Fly  1194 FLVTGLGQKIYIWQLRDGDLIGVAFI--DTNIYVHQII----TVKSLIFIADVYKSISLLRFQEE 1252
            .|....|:||.:..|   ||....|.  |..:.|...|    |.|..::.:.:..|:::.::..|
pombe   891 GLCYATGRKIGVKML---DLDSKKFCNSDCELPVRSPIVSMSTYKDYVYTSSLRDSVAVFQYDSE 952

  Fly  1253 YRTLSLASRDFNPLEVYGIE-FMVDNSNLGFLVTDAERNIIVYMYQPEARESLGGQKLLRKADYH 1316
            ..:|:|...|.:  ...||: |.:....|.| ..|.:|.:..:..:.|...|...|.
pombe   953 NNSLNLVCSDTS--SRLGIDCFYISQKKLLF-SCDKDRLLTCFKVEGEVCTSTREQM-------- 1006

  Fly  1317 LGQVVNTMFRVQCHQKGLHQRQPFLYENK--HFVVYG----TLDG 1355
            |..::.|:.:.:.:....|.:...:..:|  |.:|:|    ||||
pombe  1007 LQPILTTVSQTKTNALTNHLKYSVIRVDKDNHNIVWGLMGCTLDG 1051

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf160	NP_995833.1	SFT1	1..1453	CDD:227490	241/1410 (17%)
		MMS1_N	94..674	CDD:287414	116/668 (17%)
		CPSF_A	1086..1419	CDD:281209	56/284 (20%)
mms1	NP_592998.1	MMS1_N	80..566	CDD:287414	105/600 (18%)
		CPSF_A	826..1057	CDD:281209	52/271 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10644
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100