Protein Alignment Cpsf160 and cpsf1

DIOPT Version :9

• Sequence 1: NP_995833.1
• Gene: Cpsf160 / 44250
• FlyBaseID: FBgn0024698
• Length: 1455
• Species: Drosophila melanogaster
• Sequence 2: XP_031760511.1
• Gene: cpsf1 / 100379854
• XenbaseID: XB-GENE-5881751
• Length: 1432
• Species: Xenopus tropicalis
• Alignment Length: 1502
• Identity: 673/1502 - (44%)
• Similarity: 958/1502 - (63%)
• Gaps: 117/1502 - (7%)

  Fly     1 MFSMCKQTHSATAVEFSIACRFFNNLDENLVVAGANVLKVYRIAPNVEASQRQKLNPSEMRLAPK 65
            |:::.:|.|..|.:|||:.|.||:|.:.||||||.:.|.|||:.||.|:|.:.: ..||:: ..|
 Frog     1 MYAVYRQAHPPTGLEFSMYCNFFSNSERNLVVAGTSQLYVYRLNPNCESSSKGE-KGSEVK-GHK 63

  Fly    66 MRLECLATYTLYGNVMSLQCVSLAGAMRDALLISFKDAKLSVLQHDPDTFALKTLSLHYFEEDDI 130
            .:||.:|:::.:|||||:..|.||||.|||||:|||:|||||:::||.|..|||||||||||.::
 Frog    64 EKLELMASFSFFGNVMSMASVQLAGAKRDALLLSFKEAKLSVVEYDPGTHDLKTLSLHYFEEPEL 128

  Fly   131 RGGWTGRYFVPTVRVDPDSRCAVMLVYGKRLVVLPFRKDNSLDEIELADVKPIKKAPTAMV---S 192
            |.|:......|.|||||..||||||:||.:|||||||:|...:|.:            .:|   .
 Frog   129 RDGFVQNVHNPKVRVDPSGRCAVMLIYGTQLVVLPFRRDTLAEEHD------------GLVGEGQ 181

  Fly   193 RTPIMASYLIALRDLDEKIDNVLDIQFLHGYYEPTLLILYEPVRTCPGRIKVRSDTCVLVAISLN 257
            ::..:.||:|.:|:||||:.|::|:||||||||||||||:||.:|.|||:.||.|||.:||||||
 Frog   182 KSSFLPSYIIDVRELDEKLLNIIDMQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSIVAISLN 246

  Fly   258 IQQRVHPIIWTVNSLPFDCLQVYPIQKPIGGCLVMTVNAVIYLNQSVPPYGVSLNSSADNSTAFP 322
            |.|:|||:||::.:||:||.|...:.|||||.::..||:::|||||||||||||||..:.:|:||
 Frog   247 IMQKVHPVIWSLTNLPYDCTQALAVPKPIGGVVIFAVNSLLYLNQSVPPYGVSLNSLTNGTTSFP 311

  Fly   323 LKPQDGVRISLDCANFAFIDVDKLVISLRTGDLYVLTLCVDSMRTVRNFHFHKAAASVLTSCICV 387
            ||||:|:|::|||:...||..||:||||:.|::|||||..|.||:||:|||.||||||||:.:..
 Frog   312 LKPQEGLRVTLDCSQATFISYDKMVISLKGGEIYVLTLITDGMRSVRSFHFDKAAASVLTTSMTP 376

  Fly   388 LHSEYIFLGSRLGNSLLLHFTEEDQSTVITLDEVEQQSEQQQRNLQDEDQNLEEIFDVDQLEMAP 452
            :...|:||||||||||||.:||:.|      |.....|:...:  |||..|.::  .||.....|
 Frog   377 MEPGYLFLGSRLGNSLLLRYTEKVQ------DSPAGPSKDPDK--QDEPPNKKK--RVDSSLARP 431

  Fly   453 TQAKSRRIED-EELEVYGSGAKASVLQLRKFIFEVCDSLMNVAPINYMCAGERV----EFEEDGV 512
            ..:|...::: :|:|||||..::.. ||..:.||||||::|:.|......||..    ||:|.
 Frog   432 GGSKGNMVDEIDEIEVYGSEMQSGT-QLSTYSFEVCDSILNIGPCATASMGEPAFLSEEFQES-- 493

  Fly   513 TLRPHAESLQDLKIELVAATGHSKNGALSVFVNCINPQIITSFELDGCLDVWTVFDDATKKSSRN 577
               |..:      :|:|..:|:.|||||||....|.||::|:|||.||.|:|||..:..|:....
 Frog   494 ---PEPD------LEIVLCSGYGKNGALSVLQKSIRPQVVTTFELPGCHDMWTVISNHKKEEQEG 549

  Fly   578 D---------------QHDFMLLSQRNSTLVLQTGQEINEIENTGFTVNQPTIFVGNLGQQRFIV 627
            :               :|.|::||:.:||::|||||||.|::.:||....||::.||:|..::||
 Frog   550 EKEGETPPVEAEEDTNRHGFLILSRDDSTMILQTGQEIMELDTSGFATQDPTVYAGNIGDNKYIV 614

  Fly   628 QVTTRHVRLLQGTRLIQNVPIDVGSPVVQVSIADPYVCLRVLNGQVITLALRET---RGTPRLAI 689
            ||:.|.:|||:|...:..:|:|:|||:|..::|||||.:....|||....|:..   ..|.||..
 Frog   615 QVSPRGIRLLEGVNNLHFIPVDLGSPIVHCAVADPYVVILSAEGQVSMFVLKSADPYGKTHRLVP 679

  Fly   690 NKHTISSSPAVVAISAYKDLSGLFTV-------KGDDI--NLTGSSNS--AFGHSFGGYMKAEPN 743
            .|.|:.....|:|:..|:|:||:||.       |.|.:  |:|....:  ...||
 Frog   680 QKPTLHYQSKVIALCVYRDVSGMFTTETRSAHCKDDPMGQNMTEGEGTFPEMSHS---------- 734

  Fly   744 MKVEDEEDLLYGDAGSAFKMNSMADLAKQSKQKNS------DWWRRLLVQAKPSYWLVVARQSGT 802
              |:||:::||||:      :.::...|:..||::      |:.:.   :.:||:|.|:.|::||
 Frog   735 --VDDEDEMLYGDS------SLLSSPKKEESQKSNPPTTERDFSQH---RVEPSHWTVLVRENGT 788

  Fly   803 LEIYSMPDMKLVYLVNDVGNGSMVLTDAMEFVPISLTTQENSKAGIVQACMPQHANSPLPLELSV 867
            :|||.:||.:||:||.:...|..||.|:....|.:  |.|..|..:.     :....||..|:.:
 Frog   789 MEIYQLPDWRLVFLVKNFPVGQRVLVDSSFGQPSA--TGEGRKEEVT-----RQGEMPLVKEVLL 846

  Fly   868 IGLGLNGERPLLLVRTRVELLIYQVFRY-PKGHLKIRFRKM-DQLNLLDQQPTHIDLDENDEQEE 930
            :|||....||.|||....|||||:.|.: .:|:||:||:|: ..:|..:::|...........|:
 Frog   847 VGLGNRQSRPYLLVLVDSELLIYEAFAHESQGNLKVRFKKVPHNINFREKKPRQSKKKCEGSSED 911

  Fly   931 IESYQMQPKYVQKLRPFANVGGLSGVMVCGVNPCFVFLTFRGELRIHRLLGNGDVRSFAAFNNVN 995
            :.:...    |.:.|.|.::.|.|||.:||.:|.::.:|.||.||:|.:..:|.:.|||.|:|:|
 Frog   912 VNARGR----VARFRYFQDIFGYSGVFICGPSPHWLLVTSRGALRLHPMTIDGFIESFAPFHNIN 972

  Fly   996 IPNGFLYFDTTYELKISVLPSYLSYDSVWPVRKVPLRCTPRQLVYHRENRVYCLITQTEEPMTKY 1060
            .|.|||||:...||:|.|||:.||||:.|||||:|||||...:.||.|::||.:.|...|..|:.
 Frog   973 CPKGFLYFNRQGELRICVLPANLSYDAPWPVRKIPLRCTAHYVSYHVESKVYAVTTSVHEVCTRV 1037

  Fly  1061 YRFNGEDKELSEESRGERFIYPIGSQFEMVLISPETWEIVPDASITFEPWEHVTAFKIVKLSYEG 1125
            .|..||:||.....|.||:|.|:...|.:.||||..||.:|:..|..|.|||.|..|.|.|..|.
 Frog  1038 PRMTGEEKEFETIERDERYISPVQEAFSIQLISPLRWETIPNTRIDLEEWEHATCMKTVSLKSEE 1102

  Fly  1126 TRSGLKEYLCIGTNFNYSEDITSRGNIHIYDIIEVVPEPGKPMTKFKIKEIFKKEQKGPVSAISD 1190
            |.||||.|:.:||.....|::|.||.|.|.||||||||||:|:||.|.|.:::|||||||:|:..
 Frog  1103 TVSGLKGYIAVGTCLMQGEEVTCRGRILIMDIIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCH 1167

  Fly  1191 VLGFLVTGLGQKIYIWQLRDGDLIGVAFIDTNIYVHQIITVKSLIFIADVYKSISLLRFQEEYRT 1255
            ..|:|||.:||||::|.|:|.||.|:|||||.:|:||:|:||:.|..||:.|||||||:|||.:|
 Frog  1168 CNGYLVTAIGQKIFLWSLKDNDLTGMAFIDTQLYIHQMISVKNFILAADLMKSISLLRYQEESKT 1232

  Fly  1256 LSLASRDFNPLEVYGIEFMVDNSNLGFLVTDAERNIIVYMYQPEARESLGGQKLLRKADYHLGQV 1320
            |||.|||..|||||.:||:|||:.|||||:|.:||:|:|||.|.|:||.||.:|||:||:|.|..
 Frog  1233 LSLVSRDVKPLEVYSVEFLVDNNQLGFLVSDRDRNLILYMYLPAAKESFGGMRLLRRADFHAGSN 1297

  Fly  1321 VNTMFRVQCH--QKGLHQRQPFLYENKHFVVYGTLDGALGYCLPLPEKVYRRFLMLQNVLLSYQE 1383
            :|:.:|..|.  .:| ..|:..|::|||...:.||||.:|..||:.||.|||.|||||.|.....
 Frog  1298 INSFWRTPCRGGSEG-PSRKAVLWDNKHITWFATLDGGVGLLLPMQEKTYRRLLMLQNALTVLPH 1361

  Fly  1384 HLCGLNPKEYRTLKSSKKQGINPSRCIIDGDLIWSYRLMANSERNEVAKKIGTRTEEILGDLLEI 1448
            | .||||:.:|.|.||::...||.|.::||:|:..|..::|.||:|:|:||||.|:.||.|||||
 Frog  1362 H-AGLNPRAFRMLNSSRRMLQNPVRNVLDGELLNRYLYLSNMERSELARKIGTTTDIILDDLLEI 1425

  Fly  1449 ERLASVF 1455
            :|:.|:|
 Frog  1426 DRVTSLF 1432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf160	NP_995833.1	SFT1	1..1453	CDD:227490	671/1498 (45%)
		MMS1_N	94..674	CDD:287414	284/602 (47%)
		CPSF_A	1086..1419	CDD:281209	177/334 (53%)
cpsf1	XP_031760511.1	SFT1	1..1426	CDD:227490	669/1494 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	535	1.000	Domainoid score	I277
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40865
Inparanoid	1	1.050	1228	1.000	Inparanoid score	I186
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33701at33208
OrthoFinder	1	1.000	-	-		FOG0004621
OrthoInspector	1	1.000	-	-		oto104032
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3233
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060