DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sip1 and Gpatch8

DIOPT Version :9

Sequence 1:	NP_001285636.1	Gene:	sip1 / 44238	FlyBaseID:	FBgn0024191	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	XP_001062937.3	Gene:	Gpatch8 / 685233	RGDID:	1596463	Length:	1513	Species:	Rattus norvegicus

Alignment Length:	441	Identity:	89/441 - (20%)
Similarity:	156/441 - (35%)	Gaps:	119/441 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDNDYERFEITDYDLDNEFNINRPRGRQSRHQQIYGIWADDSEEESGGEGGTKRRGRAARKPKD 65
            :.|..|::.:..|..:::..:.::.|.:..:.::.                   .|..::|..||
  Rat   140 LCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREF-------------------ARNVSSRSRKD 185

  Fly    66 YTMPVNFVAGGIQQAGKKKKKALQADDEKGSQKEGAEA-----------------DQGEESDDSA 113
                           .||::|||:...|...|::.||.                 |.|||..|.:
  Rat   186 ---------------EKKQEKALRRLHELAEQRKQAECAPGSGPMFRPTTVAVDEDGGEEDKDES 235

  Fly   114 ASGRPAFGQNDPG-SSNSSSEEERP-TLSRKQPSTTFQHRSHIASE-------RNVGAWEQHTRG 169
            ::...|...:..| .|:.|:|:..| |..:...||.....|.:||:       .|:|...|.
  Rat   236 STNSGASAISSCGFGSDFSTEKGGPFTSVQITNSTGLSQASGLASQGISFGIKNNLGPPLQK--- 297

  Fly   170 IGAKLLLQMGYEPGKGLGKDLQGISHPVQAHVRKGRGAIGAYGPETAASIG----GKTN-----K 225
                  |.:.:...|.....|:.|:...:.|..:|....|....|.::..|    |:|:     .
  Rat   298 ------LGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKAEEKSSDQGVQKVGETDGGGNLD 356

  Fly   226 SIKVDEDVREAKEFKDQLNKW----RKGSAGGAEPMERQGKRYYYKSVEEVIAKGHTS-----GH 281
            ..|.|||.::.......|:|.    |:...|..||      .||:     .|...|..     ..
  Rat   357 GKKEDEDPQDGGSLASTLSKLKRMKREEGTGATEP------EYYH-----YIPPAHCKVKPNFPF 410

  Fly   282 LLSEKLSKKL-GNVRVIDMTGPEKRVLSGYHALGQAKIT----PEETLYDTEATEKGSAPACVFA 341
            ||..:.|::: |:.|......||.|..|.....|.:|..    .|:|:.|....:|   .|.|..
  Rat   411 LLFMRASEQMEGDHRTHSKNAPENRKGSSPRPKGCSKAAASQGAEKTVSDVSEPQK---EATVVG 472

  Fly   342 MPELTHNLQLLVSQC------EQQIIAIDNQERECSSQQAALESEHRKLEE 386
            ..|.....:  ..:|      ||.:.::    || ||:....||:.:::.:
  Rat   473 PSEPGGKTE--TKKCSGEGEGEQSVESL----RE-SSESQMCESDPKEISQ 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sip1	NP_001285636.1	TIP_N	3..93	CDD:289242	13/89 (15%)
		G-patch	167..211	CDD:279867	7/43 (16%)
		GCFC	416..685	CDD:285127
Gpatch8	XP_001062937.3	G-patch	40..82	CDD:279867
		SPEC	<94..206	CDD:295325	15/99 (15%)
		zf-C2H2_jaz	136..163	CDD:288983	3/22 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900