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Protein Alignment sip1 and tfip11

DIOPT Version :9

Sequence 1:	NP_001285636.1	Gene:	sip1 / 44238	FlyBaseID:	FBgn0024191	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	NP_001002721.1	Gene:	tfip11 / 436994	ZFINID:	ZDB-GENE-040718-479	Length:	832	Species:	Danio rerio

Alignment Length:	889	Identity:	316/889 - (35%)
Similarity:	480/889 - (53%)	Gaps:	134/889 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DYERFEITDYDLDNEFNINRPRGRQSRHQQIYGIWAD-DSEEESGGEGGTKRRGRAARKPKDYTM 68
            :.|:||::::||.||||.:|.|.||::.:..|||||: ||::|....||        ::.|||:.
Zfish    20 EIEKFEVSEWDLANEFNPDRRRYRQTKEEATYGIWAEQDSDDERPSFGG--------KRAKDYST 76

  Fly    69 PVNFVAGGIQQAGKKKKKALQADDEKGSQKEGAEADQGEESDDSAASGRPAFGQNDPGSSNSSSE 133
            ||:||:.|:::...::|          :::||::....||:.....:..|...|.  |.|..:|:
Zfish    77 PVSFVSAGLRKTAAEEK----------AEREGSDDSDAEEAPPPPRAAAPKKLQT--GGSFKTSQ 129

  Fly   134 EERPTLSRKQPSTTFQHRSHIASERNVGAWEQHTRGIGAKLLLQMGYEPGKGLGKDLQGISHPVQ 198
                           :....|.:.:::|.||:||||||.|||.:|||.|||||||:.|||.:|::
Zfish   130 ---------------RFAGGIRTGQDLGNWEKHTRGIGQKLLQKMGYVPGKGLGKNAQGIVNPIE 179

  Fly   199 AHVRKGRGAIGAYGPETAASIGGKTNKSIK----VDEDVREAKEFKDQLNKWRKGSAGGAEPMER 259
            |.:|||:||:||||.|       :|.:|::    ||.:..|.:||:.:|.:|||      ||...
Zfish   180 AKLRKGKGAVGAYGSE-------RTQQSLQDFPVVDSEEEEEEEFQKELGQWRK------EPGTA 231

  Fly   260 QGK-RYYYKSVEEVIAKGHTSGHLLSEKLSKKLGNVRVIDMTGPEKRVLSGYHALGQAKITPEET 323
            :.| :|.|::|:::.|.| |..::...:.:.:|..|:||||||.|::|.:.|..:.|....|||.
Zfish   232 KKKPKYSYRTVDDLKAHG-TRANMSMSRPAGELAQVKVIDMTGREQKVYNSYSHMSQKHSVPEEA 295

  Fly   324 LYDTEATEKGSAPACVFAMPELTHNLQLLVSQCEQQIIAIDNQERECSSQQAALESEHRKLEEIV 388
            .......|:.|:.   ||:|||.|||:||:...||.|:            |:|...:|.| :.:|
Zfish   296 PLSVSTREQKSSG---FALPELEHNLKLLIELTEQDIL------------QSARLLQHEK-DTVV 344

  Fly   389 QLERN----HIRTLEES-----LERVERLID---------NPDLSLPQAERLFRELLVDYAAEFH 435
            .|...    .:|..||.     ||:|..|::         :|.|||.:..::|.:|..::..|:.
Zfish   345 TLTHESDALQVRLAEEEETLGRLEQVMSLVERFEAGDKEGDPALSLQECAKIFEQLQTEFYQEYK 409

  Fly   436 EFGLADLAAGVIAPLLKRELVQWQPLENPTEPLPLIKKWRGMLQQGDAAEQQPRNV-FDPYSSLI 499
            ..||.|||..|:.||||.:|..|.||::.::.|..:.:||.:|:...:....|... .|||..||
Zfish   410 TMGLGDLAVSVVHPLLKEKLRNWDPLKDCSDGLEEVGQWRAILESTLSLHSGPDTTNMDPYHRLI 474

  Fly   500 WAGVMPSFRSSAAAWQPKEHPPMASLLDAWAPLLPSWVLDSVLEQLVLPRLVAGVQEWDPLTDTV 564
            |...:|..|:..:.|||:...||...::.|||:||.|:||.|||||:.|||...|..|:||||||
Zfish   475 WEVWVPVMRTCVSQWQPRNVGPMVDCVECWAPVLPLWILDHVLEQLIFPRLQREVDNWNPLTDTV 539

  Fly   565 PIDSWVLPWHAILGSKLEEAVYPQIRSKLGIALRAWSPHDRSARAMLTPWQKAFPEEEMQEFLQR 629
            ||.||:.||..::.::| |.:|..|||||..||:.|.|.|.|||.:|.||:..|.....:.|:.:
Zfish   540 PIHSWIHPWLPLMQTRL-EPLYAPIRSKLAHALQRWHPSDSSARLILQPWRDVFTPGAWEAFMVK 603

  Fly   630 YIVPKLQATLGELIINPMHQDLELWQQVWEWHELIDPMYMAQLLDRHFFPRWMQVLVVWLNQSPD 694
            .|||||...||||::||..|.|:.:..|.:|..::....|..|||::|||:|:|||..||:.:|:
Zfish   604 NIVPKLALCLGELVVNPHQQLLDPFNWVMDWECMLSVSSMVGLLDKNFFPKWLQVLCSWLSNNPN 668

  Fly   695 YAEISRWYTGWKSMLSEPLLREPSVKEHLRRALEIMHRASDT----LLQPTV------------- 742
            |.||::||.|||.:|||.||..|.|||.|..||:||:||..:    .:||..
Zfish   669 YEEITKWYLGWKGLLSENLLSHPLVKEKLNEALDIMNRAVASGLGGYMQPGARENIAYLIQTERR 733

  Fly   743 ----------------TPTPPPPVPPAPVIMMDLIHPPAQLEFKELVSQQCADLGIIFAPLPGRR 791
                            :.|.||.:...|.        .....||:||..:..:.||:|.||..:|
Zfish   734 KDFQCELQPERREVDNSATRPPGMAAVPA--------SVPTNFKDLVQAKAEENGIVFMPLVAKR 790

  Fly   792 EMGKQIYRVGKLFCYIDRHVCMVSDGSFSNWKPVSLNHLLERSQ 835
            .||||::..|::..||:|.|..|.  ....|.|.||..|::.::
Zfish   791 HMGKQLFTFGRIVIYIERGVVFVQ--GEKTWVPTSLQSLIDMAK 832

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.