DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sip1 and zgpat

DIOPT Version :9

Sequence 1:	NP_001285636.1	Gene:	sip1 / 44238	FlyBaseID:	FBgn0024191	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	NP_956779.1	Gene:	zgpat / 393457	ZFINID:	ZDB-GENE-040426-1248	Length:	504	Species:	Danio rerio

Alignment Length:	306	Identity:	81/306 - (26%)
Similarity:	124/306 - (40%)	Gaps:	79/306 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PAFGQNDPGSSNSSSEEERPTLSRKQPSTTFQHRSHIASERNVG---AWEQHTRGIGAKLLLQMG 179
            |...|:|..||:||..|:........ :..|..|....::.|..   .||.||||||:|||::||
Zfish   257 PPLRQDDVSSSSSSDSEDDAECDGGY-AKVFTSREEDLAQVNTAEFCGWEAHTRGIGSKLLMKMG 320

  Fly   180 YEPGKGLGKDLQGISHPVQAHV-RKGRG---AIGAYGPETAASIGGKTNKSIKVDEDVREAKEFK 240
            ||.||||||.|.|...||||.| .||..   .......:|||:|......|.|     |:||:
Zfish   321 YELGKGLGKTLSGRVEPVQAVVLPKGHSLDICAELTQRKTAAAIAKNNPTSHK-----RKAKK-- 378

  Fly   241 DQLNKWRKGSAGGAEPMERQGKRYYYKSVEEVIAKGHTSGHLLSEKLSKKLGNVRVIDMTGPEKR 305
                  :|.|.                          ::.|.:.:.|:.|||: |....:.....
Zfish   379 ------KKAST--------------------------STRHNVFDFLNSKLGD-RAQSASHSSSS 410

  Fly   306 VLSGYHALGQAKITPEE---TLYDTEATEKGSAPACVFAMPELTHNLQLLVSQCEQQIIAIDNQE 367
            :::|..|....|.|...   .|:  ||.||                    |:|.|::|..:....
Zfish   411 LVTGAEAYRGGKSTKRSLNVRLF--EAAEK--------------------VTQVEREIQQLTKSL 453

  Fly   368 RECSSQQAALESEHRKLEEIVQLER---NHIRTLEESLERVERLID 410
            .:.:.:.||:.|   :|||.:...|   ..::..|::::|.::..|
Zfish   454 SKRNGRDAAVVS---RLEEKLAASRKLLEQLKAQEQAIQREQKKAD 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sip1	NP_001285636.1	TIP_N	3..93	CDD:289242
		G-patch	167..211	CDD:279867	27/47 (57%)
		GCFC	416..685	CDD:285127
zgpat	NP_956779.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..121
		ZnF_C3H1	167..190	CDD:214632
		TUDOR	211..>241	CDD:119391
		G-patch	308..351	CDD:279867	27/42 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1238995at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010