DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sip1 and Zgpat

DIOPT Version :9

Sequence 1:	NP_001285636.1	Gene:	sip1 / 44238	FlyBaseID:	FBgn0024191	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	NP_001009656.1	Gene:	Zgpat / 296478	RGDID:	1310801	Length:	507	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	75/311 - (24%)
Similarity:	116/311 - (37%)	Gaps:	97/311 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 EGAEADQGEESDDSAASGRPAFGQNDPGSSNSSSEEERPTLSRKQPSTTFQHRSHIASERNVGAW 163
            :.:::|.|:.||.|.|....| ...|.|:.:|:                            ...|
  Rat   270 DSSDSDTGDASDSSYARVVEA-NTVDTGTCSSA----------------------------FAGW 305

  Fly   164 EQHTRGIGAKLLLQMGYEPGKGLGKDLQGISHPVQAHVRKGRGAIGAYGPETAASIGGKTNKSIK 228
            |.||||||:|||::||||.|||||:..:|...|:.|.|.. ||                  ||:.
  Rat   306 EVHTRGIGSKLLVKMGYEFGKGLGRHAEGRVEPIHAVVLP-RG------------------KSLD 351

  Fly   229 VDEDVREAKEFKDQLNKWRKGSAGGAEP--MERQGKRYYYKSVEEVIAKGHTSGH----LLSEKL 287
            ...::.:        .|.::|..|.:.|  ..|:..|          .:|.....    .|:|||
  Rat   352 QCAEILQ--------KKTKQGQTGASRPPRCRRRSSR----------PEGRPPPRNVFDFLNEKL 398

  Fly   288 SKKLGNVRVIDMTGPEKRVLSGYHALGQAK-------ITPEETLYDTEATEKGSAPACVFAMPEL 345
            ..::.......:..||:|....|||...||       ...||.:..|:...:|...|       |
  Rat   399 QSQVPGTPDAGVDTPERRNKDMYHASKSAKQALSLQLFQTEEKIERTQRDIRGIQEA-------L 456

  Fly   346 THN----------LQLLVSQCEQQIIAIDNQERECSSQQAALESEHRKLEE 386
            |.|          ||..:...::|:..:..||.:...:|...:: |||:.|
  Rat   457 TRNTGRHGMATAHLQEKLEGAQRQLGQLRAQEADLQRKQRKADT-HRKMTE 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sip1	NP_001285636.1	TIP_N	3..93	CDD:289242
		G-patch	167..211	CDD:279867	23/43 (53%)
		GCFC	416..685	CDD:285127
Zgpat	NP_001009656.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	88..125
		ZnF_C3H1	173..194	CDD:214632
		TUDOR	216..262	CDD:119391
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..283		4/12 (33%)
		G-patch	309..350	CDD:279867	24/59 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	359..389		7/39 (18%)
		RILP-like	388..>503	CDD:304877	27/122 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	486..507		7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1238995at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010